Pharmacology Lecture 2024 PDF
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San Lorenzo Ruiz College of Ormoc, Inc.
Rizza Caluag
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Summary
This lecture covers a comprehensive overview of pharmacology, defining drugs as substances that alter biological functions via chemical interactions with regulatory molecules. Different classifications of drugs and their effects are detailed, demonstrating how drugs can be used for prevention, diagnosis, and treatment.
Full Transcript
It is defined as the study of substances that interact with living systems through chemical processes by binding to regulatory molecules and activating or inhibiting normal body processes. is any substance that brings about a change in biologic function through its chem...
It is defined as the study of substances that interact with living systems through chemical processes by binding to regulatory molecules and activating or inhibiting normal body processes. is any substance that brings about a change in biologic function through its chemical actions It is used in: Prevention Diagnosis Mitigation Treatment/Cure Drug-Receptor Bonds Drugs bind to receptors with a variety of chemical bonds. Æ Strong covalent bonds (which usually result in irreversible action) Æ Somewhat weaker electrostatic bonds (between a cation and an anion) Æ Much weaker interactions (hydrogen bond, van der Waals interactions, and hydrophobic bonds) Functional Modifiers Replenishers Diagnostic Agents Chemotherapeutic Agents Classification of drugs according to use ¾alter or modulate the normal physiologic functions ¾Examples: 9Analgesic drugs 9Anti-pyretic drugs 9Anti-inflammatory drugs 9Anti-hypertensive drugs Classification of drugs according to use ¾Supplement endogenous substances that are lacking or deficient in the body ¾Examples: 9Hormones (Insulin) 9IV Fluids/Electrolyte/ORS 9Multivitamins Classification of drugs according to use ¾In the case of pernicious anemia which is caused by an autoimmune disease that destroys parietal cells which secretes HCl and intrinsic factor, take Vitamin B12 Note: Pernic Pernicious PPIs, H2 cious anemia may also be caused d by by Blockers, and Fish Tape worms. Classification of drugs according to use ¾ Agents used to determine the presence or absence of a condition or a diseas disease. se. ¾ Examples: 9Edrophonium 9Edroph honium ȋǯ Test) Tesst) 9Histamine 9Histammine 9some Radiopharmaceuticals Radiopharrmaceuticalss 9Bariumm sulfate 9Dobutamine 9Dobutaamine and Dipyri Dipyridamole idamole ffor or Dz Dz Stress Stress dz dz for CAD and MI. TE: Stress Test is an NOTE: NOT n electrocardiographic electrocardiograph hic test of heart function function before, beforee, during, during g, and after a controlled period and peeriod of increasingly strenuous strenuo ous exercise. exercise. Classification of drugs according to use ¾Agents used to kill or inhibit growth of cells or nucleic acid considered as foreign to the body. Selective toxicity is considered ¾Examples: 9Antineoplastics 9Anti-infectives
