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Peritoneal Dialysis and Hemodialysis PDF

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Summary

These notes cover important concepts in nephrology. They specifically discuss topics like erythropoietin, uremia, and different stages of chronic kidney disease. The notes also discuss different dialysis procedures.

Full Transcript

Erythropoietin Uremia - Occurs when waste products associated with decreased kidney function build up in the blood - “Urine in the blood” - Symptoms: cognitive dysfunction, fatigue, SOB from fluid accumulation, loss of appetite, muscle cramps, nausea and vomiting, itching, un...

Erythropoietin Uremia - Occurs when waste products associated with decreased kidney function build up in the blood - “Urine in the blood” - Symptoms: cognitive dysfunction, fatigue, SOB from fluid accumulation, loss of appetite, muscle cramps, nausea and vomiting, itching, unexplained weight loss - Uremic fetor d/t accumulation of ammonia - Uremic frost (crystalized sweat) Kidney functions: “A WET BED” A - cid-base balance W - ater balance E - electrolyte balance T - oxin removal B - lood pressure control E - rythropoietin D - Vitamin D metabolism Stages of Chronic Kidney Disease Stages 1 - Normal pero below normal ang GFR Stage 2 - Mild loss of kidney function - GFR - 89% to 60% Stage 3a - Mild to moderate kidney function loss - Gfr 59% to 45% Stage 3b - Moderate to severe kidney function loss - 44% to 30% Stage 4 - Severe loss of kidney function - GFR 29% to 15% Stage 5 - Kidney failure - GFR is lower than 15% Dialysis - procedure used to provide an artificial replacement for lost kidney function d/t renal failure - RRT or renal replacement therapy (renal dialyzer) - four main types of RRT in common use: hemodialysis (HD), peritoneal dialysis (PD) hemofiltration (HF) hemodiafiltration (HDF) Principles of Hemodialysis Diffusion - movement from higher concentration (blood) to lower concentration (dialysate). - toxins and wastes in the blood are removed - if done mabilis, pwede mag-hypotensive or mag-shock - takes 4 to 6 hours Osmosis - excess water is removed from the blood by osmosis - water moves from an area of higher solute concentration (blood) to an area of lower solute concentration (dialysate bath) Ultrafiltration - water moving under high pressure to an area of lower pressure - by a suctioning force → dialysis membrane Indications for dialysis include For patients with ACUTE kidney injury: 1. Metabolic acidosis - where correction with Sodium Bicarb is impractical or may result in fluid overload 2. Electrolyte abnormality - hyperkalemia (↑ K in blood) + AKI 3. Fluid overload that is not expected to respond to diuretics 4. Intoxication: acute poisoning w/ a dialysable drug (lithium, aspirin) 5. Complications of uremia: pericarditis (inflammation of the sac that contains the heart), encephalopathy (group of conditions that cause brain dysfunction) CHRONIC: 1. Symptomatic renal failure 2. Low GFR (glomerular filtration rate)

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