Summary

These notes detail various anatomical and physiological concepts, including vitamin D, parathyroid hormone, and related disorders. Discusses different types of fractures and spinal issues. They appear to be notes from a medical course, not a past paper.

Full Transcript

*1. VITAMIN D: Inc. Calcium via resorption in kidney* *2. Vitamin D: Inc. Phosphate via resorption in kidney* *3. PARATHYROID HORMONE: Inc. Calcium via Bone & Kidney Resorption + Vit D Synthesis* *4. PARATHYROID HORMONE: INC. Phosphate via Bone Resorption 􀃆 Dec. via Excretion* *5. ERGOCALCIFEROL...

*1. VITAMIN D: Inc. Calcium via resorption in kidney* *2. Vitamin D: Inc. Phosphate via resorption in kidney* *3. PARATHYROID HORMONE: Inc. Calcium via Bone & Kidney Resorption + Vit D Synthesis* *4. PARATHYROID HORMONE: INC. Phosphate via Bone Resorption 􀃆 Dec. via Excretion* *5. ERGOCALCIFEROL: Plant Derivative D2* *6. Cholecalciferol: Animal Derivative D3* *7. 7 dehydrocholesterol 􀃆 cholecalciferol via SUNLIGHT* *8. Cholecalciferol 􀃆 25-hydroxy via 25 hydroxylase􀃆1,25 dihydroxy via 1hydroxylase* *(PTH Activation)* *9. CALCITONIN􀃆 DECREASE Ca via Osteoclast Activity* *10. Vitamin D LIVER Disease: Reduce 25-hydroxylase activity* *11. Vitamin D KIDNEY Disease: Reduce 1-hydroxylase Activity* *12. Rickets (Vit D Def) 􀃆 BOW LEG DEFORMITY + RACHITIC ROSARY + Pigeon Chest* *13. Rickets VIT D RESISTANT 􀃆 ALOPECIA (hair loss) + ELEVATED 1,25(OH)2D (dec. Ca from* *diet)* *14. Osteomalacia (Vit D) 􀃆 Frequent Fractures* *15. HYPERvitaminosis 􀃆 Vit D Toxicity 􀃆 Enhanced Calcium absorption 􀃆 Hypercalcemia* *􀃆 Soft Tissue Calcification* *16. HYPOCalcemia (Cause) 􀃆 LOW PTH 􀃆 Hypoparathyroidism* *17. HYPOCalcemia (Cause)􀃆 HIGH PTH􀃆 Secondary HYPERParathyroidism* *18. HYPOCalcemia(Vit D Deficiency) 􀃆 Low 25hydoxyyvitamin D Level* *19. HYPO Calcemia(Renal Insufficiency) 􀃆 Low 1,25 dehydroxyvitamin D* *20. HYPOCalcemia (Parathyroidectomy) 􀃆 Low Parathormone Levels* *21. Severe HYPOCalcemia: 􀃆 Tetany 􀃆 Cardiac Arrhythmias/Breathing 􀃆 Calcium* *Gluconate IV (Immediate Treatment) or Ca supplement + Vit D* *22. HYPERCalcemia (Excessive PTH) 􀃆 HIGH PTH HIGH CA LOW PO4* *23. HYPERCalcemia (Hypervitaminosis D) 􀃆 HIGH CA HIGH PO4 HIGH 1,25(OH)2D* *􀍞B􀅽ne􀆐􀍕 M􀅽an􀆐􀍕 S􀆚􀅽ne􀆐􀍕 Abd􀅽minal G􀆌􀅽an􀆐􀍟* *24. HYPERPhosphatemia 􀃆 Poor PO4 Absorption (Vit D Deficiency) + High PO4 Excretion* *(Excess PTH)* *25. Hyperkyphosis: 􀍞Hunchback􀍟 􀃆 Increase in thoracic curvature* *26. Crush Fractrue: Compresion of vertebral body* *27. Wedge Fracture: Small fractres around vertebral body* *28. Spinal Canal Stenosis Syndrome: Hypertrophy of Ligamentum Flavum* *29. LATERAL Displaced Scapula: damaged dorsal scapular nerve / Rhomboid Maj. Min.* *30. Winged Scapula: Long Thoracic Nerve* *Created by Aadil Habibi 􀍞The􀆌e i􀆐 n􀅽 di􀆐ea􀆐e 􀆚ha􀆚 Allah ha􀆐 c􀆌ea􀆚ed􀍕 e􀇆ce􀆉􀆚 􀆚ha􀆚 He al􀆐􀅽 ha􀆐 c􀆌ea􀆚ed i􀆚􀆐 􀆌emed􀇇􀍘􀍟* *Created by Aadil Habibi 􀍞The􀆌e i􀆐 n􀅽 di􀆐ea􀆐e 􀆚ha􀆚 Allah ha􀆐 c􀆌ea􀆚ed􀍕 e􀇆ce􀆉􀆚 􀆚ha􀆚 He al􀆐􀅽 ha􀆐 c􀆌ea􀆚ed i􀆚􀆐 􀆌emed􀇇􀍘􀍟* *31. Herpes Zoster: Located at Dorsal Root Ganglion* *32. Lumbar Puncture: Between L4/L5 (Subarachnoid Space) (Past Supraspinous Ligament)* *(Incorrect Puncture 􀃆 Go through Posterior Longitudinal Ligament)* *33. Landmark for Lumbar Puncture: Highest Points of Iliac Crests (T􀆵ffie􀆌􀍛􀆐 Line􀍿* *34. Disc Herniation: Nucleus Pulposis protrustion posterolaterally into intervertebral* *foramen* *35. Spina Bifida Occulta: Tuft of hair + small dimple* *36. Spina Bifida Meningocele: protrustion of meninges through unfused vertebral arch* *37. Spina Bifida Myelomeningocoele: protrusion of meninges and CNS tissue* *38. Spina Bifida Myeloschisis: protrustion of spinal cord or spinal nerves and meninges* *39. Spinal Cord Termination: L1 / L2* *40. Laminectomy: Ligamentum Flavum* *41. Caudal Anesthetic 􀃆 Sacrial Hiatus 􀃆 Epidural Space (Given During Pregnancy)* *42. Drooping Shoulder: Damage to Spinal Accessory Nerve / Trapezius* *43. Compression of Dens/Odontoid Process: Rupture of Transverse Ligament* *44. Fracture/Compression of Pedicles: Rupture of Cruciform Ligament* *45. Hangman􀍛s Fracture: Pars Inter-articularis \~ Spondylolysis of C2 (Anterior Displacement* *= Spondylolisthesis)* *46. Whiplash: Hyperextension Injury + Torn Anterior Longitudinal Ligament* *47. Jefferson: Burst Fracture of C1/C2 ONLY 􀃆 Damage to Anterior/Posterior Arches* *48. Wedge/Compression Fracture: Loss of Height 􀍴 Vertebral Compression* *49. Chance Fracture: Transverse Fracture w. Anterior Compression of Vertebral Body @* *T12-L2 = Forward Flexion (LAP SEATBELT INJURY)* *50. Burst Fracture: Severe Compression + Vertebral Body Spread out all directions* *(Anything below C2)* *51. Spondolysis: Fracture of Superior/ Inferior Articular Process / Pars Interarticularis* *(DOG COLLAR)* *52. Spondolysthesis: Vertebra slips anteriorly* *53. Epidural Drainage: Internal Vertebral Plexus of Batson* *54. Dorsal Rami: Innervation of Deep Intrinsic Back Muscles* *55. Ventral Rami: Mixed Spinal nerves To/From all body minus back and head cranial nerve* *56. Triangle of Petit:* *Medial Border: Latissimus Dorsi* *Lateral Border: External Abdominal Oblique* *Inferior Border: Iliac Crest* *Floor: Internal Abdominal Oblique* *57. Triangle of Auscultation: Lat Dorsi + Trapezius + Scapula* *58. Indirect Inguial Hernia: Located @ Inguinal Canal* *59. Direct Inguinal Canal: Located @ He􀆐􀆐elbach􀍛􀆐 T􀆌iangle* *60. Femoral Hernia: Located below Inguinal Ligament* *61. Klippel-Feil Syndrome: Reduction/Fusion of Cervical Vertebrae 􀃆 Stiff neck + Limited* *Motion* *62. Chiari II Malformation: Herniation of medulla and cerebellum into foramen magnum* *63. Hydrocephalus: Over Production of CSF / Interference with absorption* *64. Tethered Cord Syndrome: defective closure of neural tube + Low Conus Medularris /* *Thick Filum Terminale* *65. Artery of Adamkiewicz / Great Radicular Artery: Blood Supply to Anterior/Posterior* *Spinal Arteries* *66. Dorsal Root ganglia: Neural Crest Cell* *67. Nucleus Pulposis: Remnant of Notochord* *68. Spinal Cord: Neural Tube* *69. Annulus Fibrosis: Sclerotome Component of Somite* *70. Somites: Derived from Sclerotome*

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