Summary

This document contains medical notes on various topics. It details anti-epileptic drugs and their uses in treating patients, focusing on pregnancy and breastfeeding considerations. It also discusses neurodegenerative disease treatment.

Full Transcript

Pregnancywithtonicclonic Topiramate causeof 🪢 Joc is Valproicacid follicacid Zonesemide oligohydrosis GM W I Anti-epileptics:...

Pregnancywithtonicclonic Topiramate causeof 🪢 Joc is Valproicacid follicacid Zonesemide oligohydrosis GM W I Anti-epileptics: Antiepileptic for pregnant %: Levetiracetam, lamotrigine Rash Antiepileptic for breastfeeding &: Levetiracetam Antiepileptic need renal adjustment: Topiramate Antiepileptic in absence seizures (petit): Ethosuximide younggirlor Antiepileptic for older + (AOT): Alprazolam, Oxazepam, Triazolam Boy 4315015 Status epilepsy (SE): BZDslorazepamIV DOIFirst d a.am 1st BZD: IV Diazepam, Lorazepam, midazolam 2nd: phenytoin, valproic acid, levetiracetam # Fastest Diazepam (D form Drive) # Longest Lorazepam (longest from L) lastchoice # Strongest Clonazepam phenoparpital Becauseof St M I Hypertension Treat neuropathic pain and depression: ⁉ HLAB15 IIe d É 1st: duloxetine, pregabalin for Others: Gabapentin, venlafaxine,highly CBZs,.. Stevens-Johnson Syndrome stevensonnson syndrome oxecarbamazepine J Phenytoin: hypersensitivity reaction fpiyjihf.in phenotoin Strong correlation between the plasma level and its effect Dose: phenytoin sodium 100 mg = 92 mg of phenytoin base 8381asinine m _I SE of phenytoin: Gingival hyperplasia, nystagmus, hirsutism, acne, Purple glove syndrome Rapid involuntary you movement of the eye # Topiramate: CI with alcohol, metallic acidosis, metformin Cyclosporine kidney # Carbamazepine, Oxecarbamazapin, Phenytoin, Fosphenytoine: HLA-B 1502 d ve Anti cancer pint y u Sodium Channel Blockers (Na+): - Phenytoin, Fosphenytoine B phenytoin - Carbamazepine, Oxecarbamazapin JALA it's - Lamotrigine Rash I p I does v GABA enhancing agent (GABA): 🪢 - Barbiturate. # withdrawal symptoms ucrease - Benzodiazepine (BZDs) ofGABA - Valproic acid # Used in trigeminaltha Carbamazepine yOnecarbamazepine neuroglia “‫"اﻟﺘﻬﺎب اﻟﻌﺼﺐ اﻟﺴﺎﺑﻊ‬: CBZs

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