Non-Alcoholic Fatty Liver Disease PDF
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Uploaded by naomii11
William Paterson University
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Summary
This document provides information about non-alcoholic fatty liver disease (NAFLD), covering various aspects such as its causes, effects, risk factors, and prevention. The text explains the spectrum of NAFLD, highlighting steatosis, steatohepatitis, fibrosis, and cirrhosis as stages of the condition. The document also touches on secondary and tertiary prevention measures, emphasizing a holistic approach to managing NAFLD.
Full Transcript
Non-Alcoholic Fatty Liver Disease What is it? ○ A spectrum of diseases from least severe to most severe ○ Steatosis Causes fat droplets to form and grow on hepatocytes ○ Steatohepatitis ○ Fibrosis ○ Cirrhosis Irreversible scarring of the liver usually caused by inflammation and necrosis Slow, progre...
Non-Alcoholic Fatty Liver Disease What is it? ○ A spectrum of diseases from least severe to most severe ○ Steatosis Causes fat droplets to form and grow on hepatocytes ○ Steatohepatitis ○ Fibrosis ○ Cirrhosis Irreversible scarring of the liver usually caused by inflammation and necrosis Slow, progressive chronic disease Inflammation caused by toxins or disease (ie, hepatitis, drug addiction, alcoholism) Hepatitis C a leading cause of cirrhosis and liver cancer ○ Results from fat deposition in the liver Typically affects individuals with metabolic syndrome which includes a combination of three of the five following diagnoses ○ Obesity: ○ Waist of 40”men, ○ 35” for women ○ HTN: 130/85 or higher ○ Hyperglycemia: Fasting glucose 100 mg/dl ○ Hyperlipidemia: HDL less than 40 mg/dl men, and women less than 50 dl ○ Triglycerides 150 mg/dl on medication Rapidly growing health concern Associated with aging, Type 2 Diabetes, metabolic syndrome ○ Metabolic syndrome is presence of metabolic factors that increase risk of Type 2 DM and CV disease Risk factors ○ Up to 30% of Americans may have NAFLD (American Liver Foundation, 2020) ○ Gene PNPLA3 identified as a risk factor ○ Latinos at highest risk of any ethnic group Secondary Prevention ○ Complete Blood count ○ ALK phosphate ○ Serum bilirubin ○ A1C and fasting glucose ○ Fasting cholesterol ○ AST (aminotransferese) and LDH (Lactate dehydrogenease) Tertiary Prevention ○ Medical follow up for prediabetes, hypertension, metabolic syndrome, NAFLD Possible medications to lower cholesterol/triglycerides ○ Weight loss program ○ Diet: Importance of DASH diet, portion control Who would you involve in teaching? How can this be implemented? ○ Elimination Need stool daily/ Exercise helps with this ○ Exercise: 150 minutes per week ○ Regular wt. and b/p checks ○ Periodic blood work
