Narcotic Drugs Chapter I PDF
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This document covers various aspects of narcotic drugs, including their chemical analysis, classification by origin, general effects, use, and different types of tests. It details the different methods of drug analysis and the principles behind them.
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N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs gs Color tests ru D Material Indicators Green plant material: unlikely to test for cocaine or heroin initially. tic Brownish tarry material: suggests hashish or heroin. Tan powders: often contain heroin, methamphetamine, and related substances. co Blotter papers, gel windows, tiny tablets: common for LSD. Tan or whitish powders/pills: suitable for extensive color tests. ar Note that: Some color tests involve precipitation, but not all. N Spot Plate/Test Tube gs Spot tests are performed using a glass or ceramic spot plate or a disposable test tube. Results are easier to see on a white background; some tests work ru better on a black spot plate. Procedure: D Place a small amount of the questioned powder in a well of the plate. Add the reagent. tic Use test tubes for tests requiring successive reagents or liquid– liquid extraction. Presumptive Nature: These tests react with multiple substances, but co experienced chemists can differences discern subtle. Control Samples: ar Include a blank or negative control (reagent only). Analyze known samples in parallel with the questioned material. N WHAT IS COLOR? gs Color Change indicates a chemical reaction. Color change points to an alteration in chemical bonding ru during a reaction. Colorants: Substances that absorb or emit electromagnetic D energy in the visible range; includes dyes and pigments. Mechanisms of Color Change: tic Dye Formation: Changes in molecular structure allow visible light to interact with molecular orbitals. co Transition-Metal Complexes: Alteration of d orbitals allows for visible light interactions. ar The reaction between a drug and a reagent creates an energy difference between orbitals (atomic or molecular) , N enabling visible light to promote an electron. N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs N ar co tic D ru gs gs NaOH----.... ? M icrocrysta I Tests r;--;L-]-.....- Class cylinder / M1cr-oscope ru /; SampJe shde D The precipitating reagent is placed on a coverslip and / HAuCl4 + H3 :PO4 inverted over a small portion of the sample to which a Coverslop strong base is added. tic i lm,ert Amphetamine and methamphetamine in the freebase form have sufficient vapor pressure to evaporate and co condense in the reagent. ar Nonvolatile are effectively removed from the sample. N