Cardiac Glycosides PDF

Summary

This document contains notes on tests for cardiac glycosides, including Salkauski/Liebermann tests for steroids and Keller-Kllani tests, and information on saponin glycosides.

Full Transcript

Test For Cardiac Glycosides - Salkauski/Liebermann 6....

Test For Cardiac Glycosides - Salkauski/Liebermann 6. SQuill (urginea mantimal - - scillaren - - TestFor steroids * (Lactor Ring) Butadienolidea- - In Liebermann - Expectorant unsaturated - test saturated and 11 i Results yellow Emerald green 7. Black hellebore (Helleborous niger / -Const-Hellebrin - Keller-Kllani Test - Deoxysugar. Saponin Glycosides D ↑ destroy - Kedde's test - Bitter , Sternutatory (Excessive sneezing) , hemolyze RB2 , Cardina Glycosides classifies by - - - - = Burst Lactone ring - - > RBC - - - ((-2) (Active) -. Cardenolide 9 - 15-membered - Structure : 9. Steroidal. Butadienolide b (Buposp ) - neutral. (Inactive) b. Triturpenoidal (6-membered) (C-24 double Unsaturated) - Use Sources ~ Digitoxin - Fish Poison - Destroy RBc (101d-Blooded 19 Foxglove (Digitalis purpurea (. sources : 1b Grecian Foxglove (Digitalis Kamath (. 1 Yam. (Dioscore speculipra ( digoxin Diosgenin Antinflammator - - ↳ pophilic Matagulsn Of Steroid hormones * Precursor - Digitoxin Less polar Longtalflife More toxic ( Katawan (Smilat Sarsaparilla - - - 2. spp , , - - Digoxin More polar Smilagenin & - - - - - shorter half life 3. Licorice (Glycirrhiza - - Glabra ( 2. Oleander (Nerum Oleander - Glycyrrhizin /Glymyrrhinic - - Acid Conts-Olandrin ↳ 50x as sweet as sucrose - - used to Mask he bitter taste of quinine - 3. Lily of the valley (Convallaria madalis ( - Used to treat as well - of Addison's disease - - Convallarintoxin - Increase the Foam Of beer. - 4. Dogbare /Black Indian Lemp (Aposymm Cannabium) 4. Ginseng (Panax Ginseng) - Conte - Apocynum cynarine - Gensenosides , - Panaxosides Chikusetsusaponins , - - Adaptogen - and Aphrodisiac -. Strophantus 5 ↳Stress Reliever >T Libido 5. 9. S. Kombe> K. Stophanthin 5 b.. S. Gratis-76. Strophanthin /# Orabain) G. Lactone Glycosides - Structure : Lactone : Tat : Kedde's test sources

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