Metronidazole PDF - University of Science & Technology - Aden
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University of Science and Technology – Aden
Fares Muthanna
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Summary
This document discusses metronidazole, a medication used to treat various infections, including bacterial vaginosis and more. It describes its mechanism of action, pharmacokinetics, potential side effects, and interactions with other drugs. The document is presented in a lecture format with detailed notes on metronidazole.
Full Transcript
Fares Muthanna. PhD University of Science & Technology – Aden OBJECTIVES Define metronidazole and describe its mechanism of action. Discuss the indications for using metronidazole in dental infection. Review the dosing and administration of metronidazole for dent...
Fares Muthanna. PhD University of Science & Technology – Aden OBJECTIVES Define metronidazole and describe its mechanism of action. Discuss the indications for using metronidazole in dental infection. Review the dosing and administration of metronidazole for dental infection. Identify the potential side effects and drug interactions of metronidazole. Compare metronidazole to other antibiotics that are used to treat dental infections. Discuss the role of metronidazole in preventing infection after dental surgery. INTRODUCTION Metronidazole is a synthetic antiprotozoal and antibacterial agent,( l-β-hydroxyethyl)-2-methyl-5-nitroimidazole. It belongs to the group of nitro imidazoles. Other members related to Metronidazole are tinidazole and others. Some books classified metronidazole as antiprotozoal and some as antibiotics and some others…. INTRODUCTION Metronidazole is a medication that is used to treat a variety of infections, including bacterial vaginosis, pelvic inflammatory disease, endocarditis, giardiasis, trichomoniasis, amebiasis, and dracunculiasis. Metronidazole works by disrupting the DNA of bacteria and parasites, which prevents them from multiplying and surviving. PHARMACOKINETICS Absorption Bioavailability: 80% absorption from GI tract (PO) Protein binding (
