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MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh MODULE 1 QUESTIONS WITH RATIONALE 1. The following are the Answer: D characteristic...

MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh MODULE 1 QUESTIONS WITH RATIONALE 1. The following are the Answer: D characteristics of a Liquid: Solid Liquid Gas a. Movement: Gliding Rigidity Very rigid Intermediate Negligible b. Cannot be Compress Movement Vibration Gliding Random c. Definite Shape Intermolecular Very strong Intermediate Essentially d. A and B Force of none e. B and C attraction Compressibility No effect, No effect, Can be cannot be cannot be compressed compressed compressed Volume and Definite Indefinite Indefinite Shape shape (takes (takes the the shape of shape of the the container), container definite and fills the volume volume of the container) 2. Atoms of the same # of neutrons: Answer: B a. Isotopes Isotopes à atoms of the same element having different mass b. Isotones Isotones à atoms of the same # of neutrons c. Isobars Isobar à different elements having same mass d. NOTA 3. Determine the orientation of Answer: C space of an electron: Principal quantum number (n) à size of atom; location of a. n electron from nucleus; main determinant of electron energy b. l Angular momentum/ Azimuthal quantum number (l) à shape c. ml of orbitals d. ms Magnetic quantum number (ml) à orientation in space e. NOTA Magnetic spin (ms) 4. Amount of energy required to Answer: C remove an electron from neutral Ionization energy(IE) à amount of energy required to atom to form positive atom remove an electron from neutral atom to form positive a. Electronegativity atom b. Electron Affinity Electron affinity(EA) à amount of energy release when a c. Ionization Energy neutral atom accepts an electron to form a negative ion; d. NOTA can be measured Electronegativity(EN)à ability of an atom to attract electron to itself to form bond; can only be approximate; same trend as EA and IE MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh 5. Boyle’s Law: Answer: A a. P1V1=P2V2 Boyle’s law b. T1V2=V1T2 ® Isothermal c. P1T2=T1P2 ® P1V1 = P2V2 d. NOTA Charles Law ® Isobaric ! " ® !! = "! " " Gay Lussacs Law ® Law of combining volumes ® isochoric "# ## = "$ #$ 6. A type of System that allows the Answer: B exchange of energy: Open – allows the exchange of energy and matter a. Open Close – allows the exchange of energy b. Close Isolated – impermeable to both energy and matter c. Isolated d. NOTA 7. The common bond angle of a Answer: B Trigonal Planar Shape: a. 180 b. 120 c. 90 d. 45 8. Major Extracellular Cation Answer: A a. Na INTRACELLULAR FLUID EXTRACELLULAR FLUID b. Ca Major cations Major cations c. Mg K+ Na+ d. K Mg+2 Ca+2 Major anion Major anions HPO4-2 Cl- HCO3- 9. A Vitamins that increased the Answer: C absorption of Selenium: Ca: Vitamin D a. Vitamin D Fe: Vitamin C b. Vitamin C Se: Vitamin E c. Vitamin E Zn: Pyridoxine d. Zn MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh 10. Ability to take on sufficient water Answer: C from the environment to form a Efflorescent liquid ® Loss of water of crystallization from a crystalline a. Efflorescent substance b. Hygroscopic Hygroscopic c. Deliquescent ® Ability to remove water from air Deliquescent NOTA ® Ability to take on sufficient water from the environment to form a liquid 11. The following agents can be a Answer: D treatment for ulcer, except; D – Anti-psychotic Agent a. Metronidazole TRIPLE THERAPY: b. Omeprazole OMEPRAZOLE, CLARITHROMYCIN AND AMOXICILLIN c. Mg/Al Combination d. Aripiprazole QUADRUPLE: e. NOTA TETRACYCLINE, OMEPRAZOLE, METRONIDAZOLE AND BISMUTH SALTS 12. The following are the Answer: B components of ORS, except: Oresol a. NaCl § NaCl b. CaCl2 § Trisodium citrate dihydrate c. Citrate § KCl d. Glucose § Glucose, anhydrous e. NOTA 13. Blue Vitriol: Answer: A a. Cupric Sulfate White Vitriol: Zn Sulfate b. Zinc Sulfate Green Vitriol: Fe Sulfate c. Ferrous Sulfate d. NOTA 14. The component of Aqua Regia: Answer: C a. 3HNO3:1HCl Solvents for Gold: b. 3H2SO4;1HCl Aqua Regia c. 3HCl:1HNO3 ® 3:1 (HCl:conc HNO3) d. NOTA ® best solvent for gold Selenic acid ® single acid that can dissolve gold 15. Corrosive Sublimate: Answer: C a. Hg A – Asoge/Quicksilver b. Hg2Cl2 B - Calomel, mild mercury chloride c. HgCl2 d. NOTA 16. DOC cutaneous and visceral Answer: D leishmaniasis Arsphenamine – Old Drug for Syphilis a. Arsphenamine Melarsoprol – Treatment for African Sleeping Sickness b. Melarsoprol Pen G- DOC for Syphilis c. Pen G d. SodIum Stibogluconate MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh e. NOTA 17. Pink Sulfide Answer: C a. ZnS ZnS – White Sulifde b. PbS PbS- Black Sulfide c. MnS d. NOTA 18. Central metal ion in Vitamin B12 Answer: C a. Mg Mg – Chlrorophyll b. Fe Fe- Hemoglobin c. Co d. NOTA 19. A property of carbon that shows Answer: A the ability to form chains Catenation: ability to form chains a. Catenation Isomerism: two or more compounds with the same molecular b. Isomerism formula but different structure c. Hybiridzation Hybridization: mixing of 2 or more non-equivalent atomic d. NOTA orbitals to form a new set of equivalent or degenerate hybrid orbitals 20. Configuration of Alkynes Answer: C a. Sp3 sp3 / tetrahedral shape b. Sp2 ® Configuration of alkanes c. Sp sp2 / trigonal planar shape d. Sp3d ® Configuration of alkenes sp / linear shape ® Configuration of alkynes 21. The following are criteria for Answer: C Aromaticity,except: Criteria for aromaticity: a. Cyclic ® Cyclic b. Flat or planar ® Flat or planar – sp2 hybridization (trigonal planar) c. Cumulative Double ® Conjugated alternating double bonds bonds, ® Follows Huckel’s Rule d. Follow Huckel’s Rule § 4n + 2 = number of π electrons (where n = 0, 1, 2, 3, e. NOTA any integer) 22. Complete oxidation of secondary Answer: B alcohol leads to: a. Aldehyde b. Ketone c. Carboxylic Acid d. Ester 23. Products of Combustion Answer: E '()*+,-, a. CO2 ® $% %$%&$ &⎯⎯⎯⎯⎯( $*$ (,) + %$ * (/) b. CO.%'()*+,-, ® $% %$%&$ &⎯⎯⎯⎯⎯⎯⎯( $*$ + %$ * + $* + $ (0112) c. Water MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh d. A and C e. AOTA 24. The following are cell wall Answer: B inhibitors except: B- Protein Synthesis Inhibitor a. Amoxicillin b. Tetracycline c. Aztreonam d. Imipenem 25. Glauber Salt Answer: D a. Magnesium Sulfate A- Epsom Salt b. Copper Sulfate B- Blue Vitriol c. Potassium Sulfate a. Sodium Sulfate 26. DOC for systemic acidosis Answer: A a. Sodium bicarbonate DOC for Systemic Alkalosis à NH4Cl/Vitamin C b. Potassium carbonate C/D à Used as ANTACID c. Calcium carbonate d. Magnesium hydroxide 27. Also known as oil of wintergreen Answer: B a. Benzoic Acid C à Cuticle Remover/Reagent for Shabu Manufacturing b. Methyl salicylate D à Causes hangover effect of Ethanol c. Acetone d. Acetaldehyde 28. Bordeaux mixture contains Answer: C a. Silver nitrate Components: CuSO4 + CaO b. Magnesium sulfate D à 2.5% suspension used for the topical treatment of c. Cupric sulfate seborrheic dermatitis d. Selenium sulfide 29. What group does coinage metal Answer: A belong? Group 1: Alkali metals. a. IB Group 2: Alkaline earth metals. b. IIB Group 11(1B): Coinage metals (not an IUPAC approved name) c. IIIB Group 15(5A): Pnictogens (not an IUPAC approved name) d. IVB Group 16(6A): Chalcogens. Group 17(7A): Halogens. Group 18(8A): Noble gases 30. Antifungal agent that interferes Answer: C in mitotic spindle formation: a. Amphotericin B b. Nystatin c. Griseofulvin d. Fluconazole MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh 31. A 20 Volume Hydrogen Peroxide Answer: B contains _____ H2O2: Commercial Availability a. 3% 10-volume solution (3% w/v) - Hydrogen Peroxide b. 6% Topical Solution, USP c. 9% Stabilizer: acetanilide 0.03% d. 12% 20-volume solution (6% w/v) e. 15% 32. Citric Acid, Tartaric Acid and Answer: C EDTA are what type of Antioxidant? a. True Antioxidant b. Reducing Agent c. Antioxidant synergist d. None of the above 33. The antidote for methanol Answer: E intoxication are the following Ethanol à Competitive Antagonist EXCEPT Fomepizole à Inhibits Alcohol Dehydrogenase i. Ethanol NaHC03 à Treatment for Systemic Acidosis ii. Fomepizole Methanol Intoxication à Increase in Formic Acid à Blindness iii. NaHCO3 a. I only b. II only c. III only d. II and III only e. None of the above 34. The positive result of Iodoform Answer: C test is: a. Brick red precipitate b. Silver Mirror c. Yellow precipitate d. None of the above 35. The most common reaction that Answer: C epinephrine undergoes is: Catecholamines à Catechol-O-MethylTransferases a. Glucoronidation HIP (Hydralazine/Isoniazid/Procainamide) à Acetylation b. Acetylation Morphine/Paracetamol à Glucoronidation c. Methylation d. Sulfation 36. The following are non-metals Answer: E except: Metalloids: i. Fluorine Silicon ii. Selenium Germanium iii. Germanium Polonium iv. Arsenic Antimony a. I and II Arsenic b. I and III Telurium c. I and IV Boron d. II and IV MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh e. III and IV 37. A reaction when ligands react Answer: B with a metal atom to form a coordination complex a. Precipitation b. Complexation c. Redox Reaction d. Neutralization 38. The following are amphoteric Answer: D compounds EXCEPT: Amphoteric Compounds i. Aluminum Aluminum ii. Iron Beryllium iii. Zinc Copper iv. Silver Zinc a. I and II Tin b. I and III Lead c. II and III d. II and IV e. III and IV 39. Lithium exhibits what colour of Answer: A flame in Flame Test? a. Carmine Red b. Brick Red c. Crimson Red d. Light Red 40. The following are nephrotoxic Answer: D aminoglycoside EXCEPT: a. Gentamicin b. Neomycin c. Tobramycin d. Streptomycin 41. The following statement/s is/are Answer: D FALSE except: i. Lewis Acid is Electron pair donor ii. Bronsted Lowry Base is Proton donor iii. Arrhenius Acid yields H+ a. I and II b. II only c. I only d. III only MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh e. II and III 42. The following statement/s is/are Answer: C FALSE except: i. Democritus- “atomos” ii. John Dalton- “Billiard Ball model” iii. J.J. Thomson- “Plum Pudding Model” iv. Chadwick- Proton discovery a. I and II b. I and III c. I, II and III d. III and IV e. II and III 43. Rule that states that electrons are Answer: B spread singly before pairing up Aufbau Principle/ Building Up Principle a. Aufbau Principle Electrons are placed first on the subshell with b. Hund’s Rule lowest energy level c. Pauli’s Exclusion Hund’s Rule Principle Electrons are spread singly before pairing up d. None of the above Pauli’s Exclusion Principle No 2 e- can have the same set of quantum numbers 44. The following are the Answer: C components of a Gifford’s Buffer System except: a. NaBO3 b. KCl c. NaCl d. Boric Acid 45. The following pairs are correct Answer: C except: i. Bentonite- Native colloidal hydrated aluminum silicate ii. Kaolin- Native hydrated Aluminum silicate iii. Pumice- soapclay MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh a. I only b. II only c. III only d. I and II e. II and III 46. Strong Silver Protein Answer: B a. Collargol b. Protargol c. Argyrol d. None of the above 47. This element Increase refractive Answer: C index of glass a. MnO2 b. K c. Pb d. B 48. Sugar of Lead Answer: A a. Lead Acetate b. Lead Subacetate Solution c. Lead Monoxide d. None of the above 49. Scheele’s Green Answer: B a. Cupric aceto-arsenite b. Cupric hydrogen arsenite c. 1% Potassium arsenite d. Arsenic (III) iodide MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh 50. The reaction of acid and base Answer: D yields salt and water. This reaction can be classified as: a. Combination b. Decomposition c. Single Displacement d. Double Displacement 51. Which of the following Answer: D pharmaceutical form of sulphur is crystalline in nature i. Milk of Sulfur ii. Flowers of Sulfur iii. Precipitated Sulfur iv. Washed Sulfur a. I and II b.II and III c. I and III d.II and IV e. III and IV 52. “Niton” Answer: C a. Krypton b. Argon c. Radon d. Xenon e. Helium 53. Ferric subsulfate solution Answer: D a. Basham’s Mixture b. Turnbull’s Blue c. Prussian Blue d. Monsel’s Solution MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh 54. In which of the following Answer: C containers is mephitic air stored? a. Gray b. Green c. Black d. Blue e. Brown 55. Which of the following pairs are Answer: D incorrect: i. Solvay Process- NaHCO3 ii. Haber Process- NH3 iii. Lane Process- S iv. Dow Process- H a. I and II b. II and III c. I and III d. III and IV e. I and IV 56. The following metabolic process Answer: D is undergone by Acetaminophen except: a. Glucornidation b. Oxidation c. Sulfation d. Acetylation 57. The ion that gives positive result Answer: D to Thenard’s Test causes: A à Aspirin a. Reye’s syndrome B à Mercury b. Minamata diseases C à Cupper c. Wilson’s disease D à Aluminum d. Shaver’s disease Thenard’s blue à Reaction from Aluminum heated in Sodium carbonate in Cobalt nitrate soln 58. What is the functional group for Answer: D ketones: Carboxyl group for Caboxylic acids a. Carboxyl group Hydroxyl group for alcohol b. Hydroxyl group Amino group for Amines c. Amino group d. Carbonyl group MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh 59. A preparation of 5% iodine in Answer: C water with potassium iodide: Iodine Solution: a. Iodine solution 2% Iodine in Water with Sodium Iodide b. Iodine tincture Iodine Tincture: 2% Iodine in 50% alcohol with Sodium c. Lugol’s solution Iodide d. Mayer’s reagent Mayer’s reagent: Potassium Mercuric Iodide e. Wagner’s reagent Wagner’s reagent: Iodine in Potassium Iodide 60. Give the IUPAC name of the Answer: B given chemical 5 carbon atom = “penta” CH2=CHCH2CH2CH3: 1 double bond =“ene” a. Pentene @Carbon #1 = “1” b. 1- pentene c. Pentane d. 1- pentyne e. 2- pentene 61. Produces a bluish green flame Answer: B through a cobalt glass: Through cobalt glass: a. Sodium Barium – bluish green b. Barium Sodium – Nil(pale green) c. Strontium Potassium – crimson d. Calcium Calcium – light green Strontium – purple 62. An alloy composed of 50% tin Answer: B and 50% lead: Pewter: 80% Tin & 20% Lead a. Pewter Gun Metal: 10% Tin & 90% Copper b. Solder Rose Metal: 25% Tin, 25% Lead & 50% Bismuth c. Gun metal d. Rose metal 63. What is the molecular geometry Answer: B for ammonia? Tetrahedral- Methane a. Linear Trigonal Pyramidal-Ammonia b. Trigonal pyramidal Bent-Water c. Tetrahedral Trigonal Planar- Boron Trifluoride d. Trigonal planar Bent- Ozone 64. Which of the following plant Answer: C alkaloids inhibit topoisomerase Paclitaxel- inhibit microtubules II? Vincristine-inhibiti mitotic spindle a. Paclitaxel Irinotecan- inhibit topoisomerase 1 b. Vincristine c. Etoposide d. Irinotecan 65. What acid is used in removing Answer: B the stain of mineral chameleon? A à required for the Permanganometry a. Sulfuric Acid b. Oxalic Acid c. Nitric Acid d. Hydrochloric Acid MetamoRPh Tutorials Assessment Exams 2021 Jebb Patrick M. Delos Santos, RPh 66. Alkali + Fats à Soap + Glycerol Answer: D a. Neutralization Neutralization 3456 + 7308 à 03/2 + 9328: b. Fermentation Hydrolysis 9328: + 03/2 à 3456 + 730e c. Hydrolysis Fermentation 1:,3;54 0