Bioinformatics Lesson 1 PDF

Primary goals: Data management and storage - Bioinformatics aims to develop efficient ways to store, organize, and manage these large datasets Sequence Analysis - analyzing biological sequences, such as DNA, RNA, and protein sequences Structural Biology - predict the three-dimensional str...

Primary goals: Data management and storage - Bioinformatics aims to develop efficient ways to store, organize, and manage these large datasets Sequence Analysis - analyzing biological sequences, such as DNA, RNA, and protein sequences Structural Biology - predict the three-dimensional structures of proteins and other biomolecules  Genome Annotation - used to annotate genomes, which involves identifying genes, regulatory elements, and functional elements within DNA sequences Phylogenetics and Evolution - help in reconstructing the evolutionary relationships among species based on genetic data Functional Genomics - used to study the functions of genes and proteins on a large scale (identifying gene functions, pathways, and interactions)  Drug Discovery and Design: - analyze biological data to identify potential drug targets, predict the effects of candidate drugs, and optimize their properties for therapeutic purposes Personalized Medicine - analyzing individual patients' genetic information to predict disease susceptibility, drug responses, and potential treatment strategies  Metagenomics - This field involves studying genetic material directly obtained from environmental samples. Systems Biology -Bioinformatics aids in the integration of biological data from various sources to create comprehensive models of biological systems. This helps researchers understand how individual components interact to create complex biological processes. SCOPE OF BIOINFORMATICS Xiong, 2006 The Central Dogma Replication Transcription END OF CENTRAL DOGMA