LDL Training Slide Deck PDF
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Uploaded by ThoughtfulMeitnerium
School of Medicine - AUTH
Vasileios Periklis MBA, MSc
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Summary
This slide deck, intended for internal use, discusses landiolol (Rapibloc®), a beta-1 adrenergic antagonist. It highlights its use in controlling heart rate in critical situations like sepsis and heart failure, with minimal effects on blood pressure and inotropy. The document specifies its indications for supraventricular tachycardia, rapid ventricular rate control in atrial fibrillation/flutter, and non-compensatory sinus tachycardia.
Full Transcript
For Internal Use Only Landiolol in a nutshell – USP and communication concept Vasileios Periklis MBA, MSc (owner) Senior International Product Manager Industrial Pharmacologist...
For Internal Use Only Landiolol in a nutshell – USP and communication concept Vasileios Periklis MBA, MSc (owner) Senior International Product Manager Industrial Pharmacologist School of Medicine - AUTH Rapibloc® (landiolol) Rapibloc® is a super-selective β1 intravenous (i.v.) adrenergic antagonist, with limited effect on blood pressure and inotropy Rapibloc® fulfills an unmet medical need: “The administration of a medicinal agent in life-critical conditions, where it is desirable to safely and rapidly reduce heart rate with limited effect in blood pressure and inotropy (e.g. pts in sepsis, pts with heart failure)”. Rapibloc® Indications Supraventricular tachycardia and for the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other circumstances where short-term control of the ventricular rate with a short acting agent is desirable Non-compensatory sinus tachycardia, where in the physician‘s judgment the rapid heart rate requires specific intervention In patients with impaired left ventricular function (LVEF
