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Alexandria National University

Rasha Nassra

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enzymes biochemistry medical school lectures

Summary

These lecture notes cover enzymes and their classification. The document discusses isoenzymes and their role in diagnostics. It also details examples, and the general classification of enzymes.

Full Transcript

Prof. Rasha Nassra Head of ENZYMES 4 Medical Biochemistry & Molecular Biology department Students’ learning outcomes By the end of this lecture, you should be able to: 1. Classify enzymes based on type of reaction. 1. Define isoenzymes and outlin...

Prof. Rasha Nassra Head of ENZYMES 4 Medical Biochemistry & Molecular Biology department Students’ learning outcomes By the end of this lecture, you should be able to: 1. Classify enzymes based on type of reaction. 1. Define isoenzymes and outline their use. ISOENZYMES oAct on the same substrate oGive the same product oHave quaternary structure oPresent in different tissues SO used in diagnosis of the exact site of their release in case of elevation of the enzyme o They differ in kinetics: different Km and Vmax o Differ in physical and chemical properties different in electrophoretic mobility Examples of ISOENZYMES CLASSIFICATION OF ENZYMES Oxidases Dehydrogenases Oxidoreductases Hydroxylases Oxygenase O

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