L26 Cytoskeleton & Intercellular Junctions PDF

Summary

This document appears to be a collection of questions and diagrams relating to the cytoskeleton and intercellular junctions. The questions are likely part of an examination for undergraduate-level biology, or medical school students.

Full Transcript

L 26- Cytoskeleton & intercellular junctions 1. Which of the following junctions is affected in Pemphigus Vulgaris? A. Zonula occludens B. Zonula adherents C. Desmosomes D. Gap junctions 2. Soha and Tarek are first year students in medical school, they started a debate about the stabili...

L 26- Cytoskeleton & intercellular junctions 1. Which of the following junctions is affected in Pemphigus Vulgaris? A. Zonula occludens B. Zonula adherents C. Desmosomes D. Gap junctions 2. Soha and Tarek are first year students in medical school, they started a debate about the stability of the different elements of the cell cytoskeletal elements. Soha insisted that the highest stability is for the microfilaments while Tarek was assuming the intermediate filaments. Please choose one point of view and get your evidence to continue the debate in your class with your colleagues. Adopted point of view: Explanation and evidences: 3. Name and Classify the following structures in 2 main categories; main cytoskeletal players and different cellular functions then draw a relation in between and justify your choice. 4. 2. 1. 3. 7. 5. 6. 8. 4. Mr Ahmed a 55years-old patient was diagnosed with multiple lung metastasis, the primary lesion was unknown but cytoskeleatl immunocytochemical staining of the biopsy confirmed colonic origin. Based on your prior and recent knowledge on cellular cytoskeleton how could you explain such results? 5. Identify and name the letters and numbers in each of the following photos. Then match and correlate different elements with justification 6. What is the function of the cell junction (3) shown in the previous diagram? A. forming impermeable barrier B. Help the cell adhesion to the basal lamina C. Help the cell adhesion to other cells D. coupling electrically adjacent cells 7. What is the type of the fialments labelled at (1) in the previous diagram? A. Desmin B. Keratin C. Actin D. Vimentin 8. Cytoplasmic bundles of actin filaments are attached to which of the following junctions? A. Zonula occludens B. Zonula adherents C. Desmosomes D. Gap junctions

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