Podcast
Questions and Answers
Which junction is primarily affected in Pemphigus Vulgaris?
Which junction is primarily affected in Pemphigus Vulgaris?
Which cytoskeletal element is considered to have the highest stability according to recent debates?
Which cytoskeletal element is considered to have the highest stability according to recent debates?
What type of junction helps in cell adhesion to other cells?
What type of junction helps in cell adhesion to other cells?
What type of filaments are labeled at (1) in the diagram?
What type of filaments are labeled at (1) in the diagram?
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Cytoplasmic bundles of actin filaments are primarily attached to which junction type?
Cytoplasmic bundles of actin filaments are primarily attached to which junction type?
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Study Notes
Cytoskeleton & Intercellular Junctions
- Pemphigus Vulgaris: Affects desmosomes.
- Soha vs. Tarek Debate: Soha argued microfilaments are most stable, Tarek argued intermediate filaments.
- Intermediate Filaments (IFs): Larger in size, evidence selected for debate in class.
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Cytoskeletal Classifications:
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Main Categories:
- Main Cytoskeletal players
- Cellular Functions
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Main Categories:
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Examples of Cytoskeletal structures:
- Microtubules
- Dynein
- Kinesin
- Vimentin
- Spectrin
- Tetramer
Case Study: Mr. Ahmed
- Diagnosis: Multiple lung metastasis
- Unknown Primary Lesion: Cytokeletal immunocytochemical staining confirmed colon origin
Cellular Structures Identification
- Photos: (Letters and numbers on the photos). Match with structures, with justification for each.
Cell Junction Function
- Function of Cell Junction (3): Helps cell adhesion to other cells.
Filament Types
- Filaments (1): Keratin
Actin Filament Attachment
- Actin Filament Attachment: To zonula adherens.
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Description
Test your knowledge on the cytoskeleton and intercellular junctions with this quiz. It covers topics such as the role of desmosomes in Pemphigus Vulgaris, the debate about filament stability, and the identification of cellular structures. Additionally, you'll explore case studies and the functions of cell junctions.
