L2-Salivary gland Team 443.pdf

Salivary Gland Color index: -Main text -important -female slides -male slides -Dr.note -Extra Editing File [ Gastrointestinal & Nutrition Block | Histology ] Objectives At the end of this lecture, you should be able to answer the following (objectives): ● Describe the microscopic structure of th...

Salivary Gland Color index: -Main text -important -female slides -male slides -Dr.note -Extra Editing File [ Gastrointestinal & Nutrition Block | Histology ] Objectives At the end of this lecture, you should be able to answer the following (objectives): ● Describe the microscopic structure of the major salivary glands in correlation with function. Table of contents: Duct system of salivary glands Types of salivary glands Major salivary glands cells of salivary Acini Types of salivary Acini This lecture was presented by: Dr. Mohammed Atteya Prof. Raeesa Abdultawab Types of salivary glands: 01-Major Salivary glands: ● Including: Parotid - Submandibular - Sublingual ● Capsulated 02-Minor Salivary glands: Within organs/tissues ● ● ● ● Including: Labial - Lingual - Buccal - Palatine Produce 5% of salivary output. Most of them are pure mucous or seromucous glands. Not capsulated Major Salivary Glands General structure Stroma Parenchyma (Supporting element) Reticular C.T. C.T. capsule. (functional element) Acini Sac-like Secretory unit C.T. septa dividing the glands into lobes and lobules. Duct system Types of Salivary Acini Serous Acini Mucoserous (Mixed) Acini Mucous Acini Lubricate food bolus ● Mucous acini with a cap ● Contain only serous cells. ● Contain only mucous cells. of serous cells (serous ● Small, spherical, and with ● Larger, more tubular, and demilunes). (‫)ﺷﻛل ھﻼل‬ a narrow lumen. with a wider lumen ● Secrete serous secretion rich in enzymes, such as ● Secrete mucous secretion. amylase and lysozyme. parts that contain mucous acini ● Serous = thin fluid rich in ● The needs to be wet to avoid getting injured. enzymes Cells of Salivary Acini Serous cells Mucous cells Myoepithelial cells (basket cells) – Pyramidal or cuboidal. – Contractile cells that embrace – Nuclei are flattened and basal the basal aspect of the acini. (flattened due to mucosal – Their contraction releases the compression), (more basal) secretion into the duct system. – Cytoplasm: Pale basophilic and Contract to squeeze the secretion out of acini vacuolated (foamy) (due to dissolved mucinogen secretory high enzyme level with apical acidophilic secretory granules). granules (rich in salivary amylase) (contain basic amino acid). – Pyramidal in shape. -Male doc said know why its basophilic – Nuclei are round and basal – Cytoplasm: Deeply basophilic (due to numerous RER) high RER due to Duct system of Salivary Glands Intralobular ducts ( prominent) ● intercalated ducts : lined by small cuboidal cells. ● Striated ducts: lined by low columnar cells. Interlobular ducts ● lined by simple columnar epithelium. ● lined by stratified columnar epithelium which becomes stratified squamous (nonkeratinized) in the distal end. Main duct Serous= Dark Mucous= Light Major salivary glands Parotid Gland ● The largest salivary gland. ● Produces 30% of salivary output. ● Purely serous. ● Prominent intralobular ducts. ● Secretion rich in: Amylase, Lactoferrin, Lysozyme,Secretory IgA (manufactured by plasma cells located in the connective tissue) Submandibular Gland ● Produces 60% of salivary output. ● Mixed but mostly serous (90%). ● Mucous acini are capped by serous demilunes. Sublingual Gland ● The smallest salivary gland. ● Produces 5% of salivary ● Mixed but mostly mucous. ● Mucous acini are capped by serous demilunes. MCQs 01 Which of the following are major salivary glands? A- Labial gland 02 C-Serous and B- Enzyme-rich mucous secretion secretion BSubmandibular gland C-Sublingual gland D-None of the above D-None of the above What type of cells line the intercalated ducts in the duct system of salivary glands? A- Simple B- Low C-Small columnar cells squamous cells cuboidal cells 05 D-Parotid and Sublingual Which salivary gland is predominantly mucous? A- Parotid gland 04 C-Lingual and Buccal What is the composition of the secretion produced by serous acini? A- Mucous secretion 03 B- Palatine gland D-Stratified squamous cells Which salivary gland produces the highest percentage of salivary output? A- Parotid gland BSubmandibular gland Answer key: D, B, C, C, B C-Sublingual gland D-Minor salivary glands This Lecture is done by: Members ● ● ● ● ● ● ● ● ● ● Hamad Alyahya Abdullah Alahedib Khalid AlRasheed Faisal Alzuhairy Abdullah Aldhuwaihy Fahad Almughaiseeb Abdulrahman Alosleb Abdulrahman Alomar Omar Banjar Yousof Badoghaish ● ● ● ● ● ● ● Waad Alanazi Raghad Almuslih Reema Alzughaibi Retal Alshohail Raghad Alothman Jouri Almaymoni Shaden Alhazzani Leaders ● Khalid Alanezi ● Waad alqahtani Reviewed by ● Academic leaders Cantact us: