Ipratropium Bromide PDF

GENERIC NAME ipratropium bromide TRADE, BRAND, OR PROPRIETARY NAME • Atrovent® CLASSES • Anticholinergic • Bronchodilator STANDARD SUPPLY • Premixed solution in a unit dose MECHANISMS OF ACTION • Blocks acetylcholine receptors on bronchial smooth muscle • Dilates the larger airways resulting in bro...

GENERIC NAME ipratropium bromide TRADE, BRAND, OR PROPRIETARY NAME • Atrovent® CLASSES • Anticholinergic • Bronchodilator STANDARD SUPPLY • Premixed solution in a unit dose MECHANISMS OF ACTION • Blocks acetylcholine receptors on bronchial smooth muscle • Dilates the larger airways resulting in bronchodilation INDICATIONS • Asthma • Bronchospasm associated with chronic bronchitis and emphysema CONTRAINDICATION • Known hypersensitivity to the drug ADVERSE REACTIONS/SIDE EFFECTS • Tachycardia • Tremors • Palpitations • Nervousness • Anxiety • Headache • Nausea • Vomiting ROUTE OF ADMINISTRATION • Nebulized for inhalation ONSET OF ACTION • 1 to 3 minutes IPRATROPIUM BROMIDE 1 ADULT DOSAGES • 500 mcg (0.5 mg) in 2.5 mL normal saline (unit dose) via small volume nebulizer (SVN) • In-line with a bag-valve mask (BVM): 500 mcg (0.5 mg) in 2.5 mL normal saline (unit dose) via SVN • May repeat the dosage PEDIATRIC DOSAGES • 500 mcg (0.5 mg) in 2.5 mL normal saline (unit dose) via small volume nebulizer (SVN) • In-line with a bag-valve mask (BVM): 500 mcg (0.5 mg) in 2.5 mL normal saline (unit dose) via SVN • May repeat the dosage SPECIAL CONSIDERATIONS • The drug may be used in conjunction with albuterol (Proventil®) • The peak effect of the drug is 1½ to 2 hours • The duration of the drug is 4 to 6 hours IPRATROPIUM BROMIDE 2