Introduction to Haematology and Anaemia PDF RCSI

RCSI Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn Introduction to Haematology and Anaemia Class Year 1 Course Pathology Lecturer Professor Siobhan Glavey...

RCSI Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn Introduction to Haematology and Anaemia Class Year 1 Course Pathology Lecturer Professor Siobhan Glavey Professor Abdullah Darwish Date 1st October 2023 LEARNING OUTCOMES Define anaemia. Describe the function of the bone marrow. Describe the clinical consequences of anaemia. Describe the classifications of anaemia, laboratory and pathophysiological Describe the causes of macrocytic, microcytic and normocytic anaemia Describe the laboratory investigations and the significance of abnormal results in the diagnosis of anaemia. Describe the causes of Fe, B12 and Folate deficiency. Describe the causes of marrow replacement/reduced function. ANAEMIAS Today’s lecture will outline some types of anaemia other than haemolytic anaemias Fe deficiency B12 deficiency Folate deficiency Aplastic anaemia Definition of anaemia: Reduction in Haemoglobin due to a disorder of globin or heme Haemoglobin < 12g/dL in non pregnant women Haemoglobin < 13g/dL in men BLOOD IS MADE IN THE BONE MARROW GENERATION OF BLOOD CELLS ANAEMIA Anaemia is a condition in which the number of red blood cells or their oxygen-carrying capacity is insufficient to meet physiological needs which vary by age, sex, altitude, smoking and pregnancy status The WHO criteria for anaemia is Haemoglobin levels