Summary

This sheet provides information on medications, such as GLP-1 and Semaglutide, used for the treatment of type 2 diabetes and weight management. It discusses various aspects, including dosage, side effects, and benefits. The document is focused on medical knowledge and not on any specific exam.

Full Transcript

IMPORTANT INFORMATION GLP1- is a hormone that regulates blood sugar, appetite, and digestion. GLP1 Is released by the gut after eating and enhances insulin secretion to control blood sugar levels. GLP-1RAs activate the GLP-1 receptor, which reduces blood sugar and energy...

IMPORTANT INFORMATION GLP1- is a hormone that regulates blood sugar, appetite, and digestion. GLP1 Is released by the gut after eating and enhances insulin secretion to control blood sugar levels. GLP-1RAs activate the GLP-1 receptor, which reduces blood sugar and energy intake. They also slow down how quickly food leaves the stomach and increases metabolism. Tirzepatide- Tirzepatide is an antidiabetic medication used for the treatment of type 2 diabetes and for weight loss. Tirzepatide is administered via subcutaneous injections. Tirzepatide It is sold under the brand names Mounjaro for diabetes treatment, and Zepbound for weight loss. Semaglutide- is an antidiabetic medication used for the treatment of type 2 diabetes and an anti-obesity medication used for long-term weight management. It is a peptide similar to the hormone glucagon-like peptide-1, modified with a side chain. It can be administered by subcutaneous injection or taken orally. Semaglutide is also commonly found in Mounjaro, Ozempic, Rybelsus, and Wegovy. Medication delivery- The Medication is delivered through fedex , it comes chilled , and theyll receive it in 1 to 3 days after being approved by the dr. How long does it take to be approved ? around 24hrs Side effects- (Tirzepatide), nausea, vomiting, and diarrhea. (Semaglutide), rapid heartbeat that doesn't decrease when rested, dehydration, dizziness, rashes, itching, and swelling around the face. How many times a week do they need to administer the injection: 1 Different types of medication form - Semaglutide oral , Semaglutide injection , Trizepatide injection Cancelations- For cancels everything is processed through customer support on the app. Anything related to customer service- direct them to the app/portal and they'll be able to receive support through there. Semaglutide Important Facts Side effects Nausea - Often occurs at the start of treatment but tends to improve over time. Vomiting - Can accompany nausea. Diarrhea - Common digestive reaction. Constipation - May occur in some patients. Abdominal Pain - Stomach discomfort or cramping. Fatigue - Feeling unusually tired or fatigued. Dizziness - Particularly during the initial dose adjustments. Benefits of Semaglutide: Semaglutide offers several benefits, particularly for people using it for weight loss and the management of type 2 diabetes. Here are the primary benefits: 1. Weight Loss Significant Weight Reduction: Clinical trials have shown that semaglutide can lead to considerable weight loss when combined with a healthy diet and regular physical activity. It's often used for patients with obesity or those who are overweight with additional health concerns. Appetite Control: Semaglutide works by mimicking the hormone GLP-1, which helps regulate appetite. It slows down gastric emptying, helping individuals feel full longer, which can reduce calorie intake. 2. Blood Sugar Control Lower Blood Sugar Levels: Semaglutide helps improve blood glucose levels by stimulating insulin secretion when blood sugar is elevated. This is particularly beneficial for people with type 2 diabetes. Reduced Risk of Hypoglycemia: Because semaglutide enhances insulin release only when blood sugar is high, the risk of low blood sugar (hypoglycemia) is lower compared to other diabetes treatments. Cardiovascular Benefits Reduced Risk of Heart Disease: Studies have demonstrated that semaglutide can reduce the risk of cardiovascular events like heart attacks and strokes in people with type 2 diabetes who are also at high cardiovascular risk. Improved Blood Pressure: Semaglutide has been associated with modest reductions in blood pressure, which contributes to overall heart health. 4. Sustainable Results Long-Term Efficacy: Research indicates that people using semaglutide can sustain weight loss and blood sugar control over an extended period when combined with lifestyle modifications. Convenient Dosing: Available in both weekly injections and a daily oral form, making it more manageable for patients to adhere to treatment. 5. Lower HbA1c Levels For people with type 2 diabetes, semaglutide effectively lowers hemoglobin A1c (HbA1c), a key marker for long-term blood sugar control, often bringing levels down to a target range. Overall, semaglutide offers a multifaceted approach to managing weight and blood sugar levels, improving both metabolic and cardiovascular health. Injectable Tirzepatide- Program Concentration Amount Patient Price Dosage name Tirzepatide 10mg/ml 1ml $397 2.5mg/25 level 1 Units per week, 4 week supply Tirzepatide 10mg/ml 2ml $497 5mg/50 units level 2 per week, 4 week supply Tirzepatide 10mg/ml 3ml $597 7.5 mg/75 level 3 Units per week, 4 week supply Tirzepatide 10mg/ml 4ml $697 10mg/100 level 4 Units per week, 4 week supply Tirzepatide 10mg/ml 5ml $797 12.5mg/125 level 5 Units per week, 4 week supply (2 shots) Tirzepatide 10mg/ml 6ml $897 15 mg/150 level 6 Units per week, 4 week supply (2 shots) Injectable Semaglutide - Program Concentration Amount Patient price Dosage name Semaglutide 2.5 mg/ml 0.5 ml (some $297 0.25 mg/10 pharmacies will level 1 fill 1 ml) Units per week, 4 week supply Semaglutide 2.5 mg/ml 1 ml $297 0.5 mg/20 level 2 units per week, 4 week supply Semaglutide 2.5 mg/ml 2 ml $297 1 mg/40 units level 3 per week, 4 week supply Semaglutide 2.5 mg/ml 3 ml $345 1.7mg/70 level 4 units per week, 4 week supply Semaglutide 2.5 mg/ml 4 ml $397 2.4mg/100 level 5 units per week, 4 week supply WEEKS & DOSAGE WEEK 1/4 =.25mg = 10 units WEEK 5/9 =.50mg = 20 units WEEK 10/13 = 1.0mg= 40 units (86% of ppl) &(diabetic patients) 14-17= 1.7mg 17= 2.4mg How Quickly Semaglutide Actually Works If You're Trying To Lose Weight How fast does semaglutide work? And when will the number on the scale realistically start to change? The answer to that question depends on a number of factors, from your genetics to your age to your sex. But, for most people, effects of semaglutide medications show up faster than you'd think. People can lose on average anywhere from five to 20 percent of their weight on these drugs in one year, depending on their starting point, research has found. When is the earliest you'll start seeing results? Will you notice changes in a week, or how about in four weeks, when you're typically eligible to increase your dose? Semaglutide medications are typically injections taken once a week, and you might start to notice effects as soon as the first dose Certain factors can impact how quickly semaglutide works. Like any med, results aren't one-size-fits-all, so the timing of your results will probably differ METABOLISM Conditions like fatty liver disease, diabetes, and high blood sugar can make weight loss more complex because there is already some level of metabolic dysfunction. AGE As you age, your metabolism slows, which may play a role in how quickly semaglutide works in your body. PERIMENOPAUSE AND MENOPAUSE Menopause might decrease how fast you are able to lose weight, BIOLOGICAL SEX Women might be more likely to lose more weight on semaglutide medications than men,This could have to do with differences in hormones, which play a big role in weight loss, or the fact that women tend to be smaller than men, according to experts. It also could be because women tend to have more body fat, and therefore have more to lose in the first place or that they tend to be more insulin resistant How quickly can you notice results with Trizepatide Tirzepatide starts working almost immediately on the molecular level, starting from your first dose. However, you won’t notice any changes in your weight for a while. Based on the results of clinical trials, Tirzepatide’s work on lowering the body’s weight becomes visible after four weeks of being on the medication. You should be willing to wait up to a year to see really tangible results in the mirror. This means losing around 15-20% of your starting weight. However, you may notice smaller changes in your weight a lot earlier. Factors Influencing the Speed of Weight Loss With Tirzepatide The speed of weight loss when using Tirzepatide will vary from one individual to another. Some of the factors that determine how much weight you’ll lose include the following,your dosage , level of adherence , initial body weight , and your lifestyle changes.

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