Diabetes Medications PDF

HypoBS DM Oral Risk? Adverse Contra- Drugs MOA Notes Agents...

HypoBS DM Oral Risk? Adverse Contra- Drugs MOA Notes Agents Weight Effects indications Gain? ⚠ Renal Titrate to Ô appetite, Issues! à Met. avoid GI Prevents ↑ Low Risk Diarrhea, issues Biguanides Metformin in glucose bloating, Acidosis good for levels Wt-LOSS upset ⚠ Heart pts w/ odd stomach Failure schedules ❌ Prego 2nd Glimepiride ↑ insulin HIGH RISK ❌ Breastfeed Only works in (Amaryl) release Generation Glipizide from Hypoglycemia ❌ Alcohol! DM2 not Sulfonylureas Wt-GAIN ⚠ DM1 (Glucotrol) pancreas Liver/Kidney Rapid ↑ Nateglinide insulin ⚠ TAKE Meglitinides (Starlix) ❌ Heart release HIGH RISK Edema WITH (Glinides) Repaglinide Failure from MEALS!!!! (Prandin) pancreas ❌ Heart Thiazoli- Pioglitazone Failure 2/2 ↑ risk of dinediones (Actos) Ô insulin fluid retention Add-on to ? bladder (TZDs, Rosiglitazone resistance ❌ Bladder metformin cancer glitazones) (Avandia) ❌ Osteoporosis Gas, cramps, Not often Acarbose Delays bloating, used d/t GI α-Glucosidase (Precose) absorption Low Risk diarrhea, ⚠ Liver SE Inhibitors Miglitol of dietary (by itself) anemia Watch liver (Glyset) carbs Liver fxn dysfunction Add-on to ↑ incretin DPP-4 metformin hormone Sitagliptin Low Risk URI, HA ⚠ Monitor Inhibitors (Januvia) fxn (by itself) Pancreatitis Pancreatitis! lipid lvls in (gliptins) (Ô Blood uncontrolled Glucose) pts ♀ yeast Sodium- Ô infections ⚠ diuretics Diuretic Glucose Canagliflozin absorption UTIs, ↑ pee ⚠ rifampin, Wt-LOSS effect à Cotransporter (Invokana) of filtered Postural phenytoin, dehydration 2 Inhibitors glucose hypoTN (esp phenobarbital w/ diuretics) Exenatide ↑ incretin Glucagon-like (Byetta) hormone Low Risk ❌ Prego Peptide-1 Liraglutide fxn – (by itself) ❌ Renal Add-on only NVD Receptor (Victoza) ↑ insulin, issues IM Agonists (GLP- Dulaglutide Ô Wt-LOSS ⚠ Renal risk (Trulicity) appetite This study source was downloaded by 100000882103000 from CourseHero.com on 11-29-2024 11:20:49 GMT -06:00 https://www.coursehero.com/file/148712605/DM-Med-Chartpdf/  1, or Incretin (Ô Blood ⚠ Mimetics) Glucose) Pancreatitis Name Onset Peak Duration Notes Humalog (lispro) Rapid Novolog (aspart) < 15 min 30-90 min 3-5h With meals Apidra (glulisine) Short Humulin R With meals 30-45m 2-3h 6.5h (Regular) Novolin R (Mix R + N only) Intermediate Humulin N Not with meals 1-3h 5-8h 14-18h (NPH) Novolin N 2-3x a day This study source was downloaded by 100000882103000 from CourseHero.com on 11-29-2024 11:20:49 GMT -06:00 https://www.coursehero.com/file/148712605/DM-Med-Chartpdf/  Lantus (glargine / U- Long Typically taken 100) 1-2h – 24 hours (Basal) at night Levemir (determir) Toujeo (glargine / U- Great for Ultra-Long 300) 1-2h – Up to 40 hrs extremely hard Tresiba (degludec) to control pts This study source was downloaded by 100000882103000 from CourseHero.com on 11-29-2024 11:20:49 GMT -06:00 https://www.coursehero.com/file/148712605/DM-Med-Chartpdf/ Powered by TCPDF (www.tcpdf.org)