Immune System PDF

Immune System 1 Immune System Immune System Introduction Innate (Nonspecific) Immunity – External Defenses – Inflammation – Interferon – Natural Killer Cells – Complement Adaptive Im...

Immune System 1 Immune System Immune System Introduction Innate (Nonspecific) Immunity – External Defenses – Inflammation – Interferon – Natural Killer Cells – Complement Adaptive Immunity – Antibody- mediated Immunity – Cell-mediated immunity 2 1  The Immune System Tonsil The Immune System helps to guard against disease and tissue Thymus damage Lymph node Immune cells are distributed Spleen throughout the body, but are Lymphatic vessel highly concentrated in blood and lymphatic tissue. Peyer’s patches Functions: Appendix – Defense: against invading microorganisms Bone – Clean up: and removes damaged marrow tissue – Surveillance: identifies and destroys abnormal body cells. 3 Lymphoid Tissue Tonsil Bone Marrow: site of white blood cell production Thymus Lymphatic Vessels: carry lymph from Lymph tissues to lymph nodes and lymph organs node before returning to blood Spleen Lymph Nodes, Tonsils, MALT, appendix: Lymphatic vessel collections of lymphocytes for immune response and macrophages to remove Peyer’s debris patches (MALT) Spleen: replaces worn out blood cells, Appendix collections of lymphocytes for immune response and macrophages to remove Bone debris marrow Thymus: site of T-lymphocyte (T-cell) maturation 4 2  White Blood Cells White Blood Cells (leukocytes) Less than 1% of total blood volume General Functions: major cells of the Immune System internal defense Plasma against foreign cells, remove debris, 55% of destroy cancer cells whole blood 5 types: – Neutrophils Buffy coat: – Lymphocytes platelets and – Monocytes leukocytes – Eosinophils (