Immunology Chapter 2 PDF

Multiple Choice Questions (MCQs) 1. **Where do naïve lymphocytes encounter antigens and initiate immune responses?** - A) Primary lymphoid organs - B) Peripheral lymphoid organs - C) Bone marrow - D) Thymus 2. **Which type of lymphocyte is responsible for humoral immunity?** - A) T lymph...

Multiple Choice Questions (MCQs) 1. **Where do naïve lymphocytes encounter antigens and initiate immune responses?** - A) Primary lymphoid organs - B) Peripheral lymphoid organs - C) Bone marrow - D) Thymus 2. **Which type of lymphocyte is responsible for humoral immunity?** - A) T lymphocytes - B) B lymphocytes - C) Natural killer (NK) cells - D) Dendritic cells 3. **Where do T lymphocytes mature?** - A) Bone marrow - B) Thymus - C) Spleen - D) Lymph nodes 4. **Which subset of T lymphocytes is involved in helping other immune cells?** - A) Cytotoxic T lymphocytes - B) Helper T lymphocytes - C) Regulatory T lymphocytes - D) Memory T lymphocytes 5. **What is the role of antigen-presenting cells (APCs)?** - A) Secreting antibodies - B) Phagocytosing microbes - C) Capturing antigens and displaying them to T lymphocytes - D) Producing cytokines 6. **Which organ is the major site of immune responses to blood-borne antigens?** - A) Thymus - B) Bone marrow - C) Spleen - D) Lymph nodes 7. **Which type of cell in the skin is specialized for antigen capture and presentation?** - A) Keratinocytes - B) Melanocytes - C) Langerhans cells - D) Intraepithelial T lymphocytes 8. **What are Peyer’s patches and where are they found?** - A) Aggregations of lymphoid tissue in the lungs - B) Aggregations of lymphoid tissue in the liver - C) Aggregations of lymphoid tissue in the small intestine - D) Aggregations of lymphoid tissue in the spleen 9. **What is the process by which lymphocytes selectively enter lymph nodes or other body tissues?** - A) Lymphocyte homing - B) Lymphocyte recirculation - C) Clonal expansion - D) Antigen presentation 10. **Which cells are primarily involved in the adaptive immune response and have the ability to remember past infections?** - A) NK cells - B) Monocytes - C) Memory lymphocytes - D) Dendritic cells 11. **What is the major site of T cell development/maturation?** - A) Bone marrow - B) Spleen - C) Lymph nodes - D) Thymus 12. **Which cells in the lymph nodes are primarily located in the primary follicles?** - A) Naïve B lymphocytes - B) Plasma cells - C) T lymphocytes - D) Dendritic cells ### True/False Questions 1. Naïve lymphocytes are mature lymphocytes that have not yet encountered an antigen. 2. Follicular dendritic cells (FDCs) are related to dendritic cells and found in lymphoid follicles. 3. B cells differentiate into plasma cells which secrete antibodies. 4. The thymus is the site of B cell maturation. 5. Lymph nodes filter blood and antigens are transported to lymph nodes mainly via lymphatic vessels. 6. Chemokines are involved in directing the migration of lymphocytes to specific areas within lymph nodes. 7. The spleen is the major site for the phagocytosis of antibody-coated microbes. 8. The mucosal surfaces of the GI and respiratory tracts are involved in immune responses to ingested and inhaled antigens. 9. The process of generating blood cells is called hematopoiesis and occurs primarily in the liver and spleen after birth. 10. Natural killer (NK) cells express CD16 (Fc receptor). ### Answer Key **MCQs:** 1. B 2. B 3. B 4. B 5. C 6. C 7. C 8. C 9. A 10. C 11. D 12. A **True/False:** 1. True 2. False 3. True 4. False 5. False 6. True 7. True 8. True 9. False 10. True