Quiz 1 Immunology Study Guide PDF
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Uploaded by HerbalAlchemist
Lake Erie College of Osteopathic Medicine
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Summary
This document is a study guide for immunology, focusing on quiz 1 material. It covers key topics like lymphocytes, MHC molecules, complement system functions, and immune system components. The guide is well-organized and provides detailed information for studying.
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Quiz 1 Immunology Study Guide 1. Lymphocytes NK has no Ag-specific receptor, innate immunity lymphocyte B cells display BCR on their surface; have MHC I and MHC II Cytotoxic T cells display TCR and CD8 molecules on their surface Helper T cells display TCR and CD4 molecules on their surface 2. All...
Quiz 1 Immunology Study Guide 1. Lymphocytes NK has no Ag-specific receptor, innate immunity lymphocyte B cells display BCR on their surface; have MHC I and MHC II Cytotoxic T cells display TCR and CD8 molecules on their surface Helper T cells display TCR and CD4 molecules on their surface 2. All nucleated cells have MHC I 3. MHC II present in: B cell, Macrophage, Dendritic cell 4. Basophil & mast cell- degranulation with IgE, release histamine and other effectors, Type I hypersensitivity 5. Eosinophil- antiparasitic activity 6. Neutrophil, innate immunity, major phagocyte, most common WBC 7. Extravasation enables WBCs to leave the blood vessels. Its deficiency increases susceptibility to bacterial infections. 8. Opsonization and its relation to phagocytosis. - Innate immunity opsonins:C3b, C4b (Complement), CRP (produced by hepatocytes) - Adaptive immunity opsonin: IgG 9. Benefits and harmful effect of the immune system 10. Functions of split-products of complement? - C3a: Anaphylatoxic - C3b: Opsonin - C4b: Opsonin - C5a: Anaphylatoxic and chemotactic for neutrophils - C5b: Component of MAC - MAC [C5b678(9)6] as the final product of complement 11. Know C3 convertases from the alternative and the classic pathways of complement; and C5 convertases. 12. Activators of the classic and alternative pathways of C. 13. Antigen-dependent and Ag-independent processes in B cell development, such as clone selection, proliferation, and Ag specificity 14. Natural defense mechanisms: - Acidic pH of the stomach - Skin - Lysozyme - Microflora - Enzymes, etc. 15. Compare Acquired immune system and Innate immunity in terms of Ag-receptors, specificity, and memory 16. Humoral adaptive immunity, IgG, and its producing cell; and Cell-mediated adaptive immunity (Tc, T helper)
