Organic Chemistry Reactions PDF
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Uploaded by SparklingSeaborgium4190
University of Oklahoma
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Summary
This document describes various organic chemistry reactions and mechanisms. It details alkylation, Grignard and Wittig reactions, reactions of aldehydes and ketones, carboxylic acids and derivatives, alkynes, alkenes, and aromatic reactions, along with nitrile reactions.
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## Organic Chemistry Reactions ### Alkylation - **Br2 or NBS, UV** -> **Br** - **RNa** -> **R-OH** - **PBr3** -> **Br** - **TsCl, NEt3 or Pyridine** -> **OTS** - **HBr**-> **Br** - **SOCI2, NEt3 or Pyridine** -> **Cl** - **NaNH2** -> **R** - **H3PO4, H2SO4** -> **R** - **H3O+ or H+, ROH** -> **O...
## Organic Chemistry Reactions ### Alkylation - **Br2 or NBS, UV** -> **Br** - **RNa** -> **R-OH** - **PBr3** -> **Br** - **TsCl, NEt3 or Pyridine** -> **OTS** - **HBr**-> **Br** - **SOCI2, NEt3 or Pyridine** -> **Cl** - **NaNH2** -> **R** - **H3PO4, H2SO4** -> **R** - **H3O+ or H+, ROH** -> **OH or OR** ### Grignard and Wittig Reactions - **Mg or Li** -> **R-MgBr or R-Li** - **Cul** -> **R-Br** - **2 eq R-Li (R2CuLi)** -> **R-R** - **R-MgBr or R-Li & R-Br** -> **R-R** - **R-MgBr or R-Li & 2 eq R-MgBr** -> **R-OH** ### Aldehydes and Ketones - **NaNH2 or NaH** -> **R-C≡C-Na+** - **R-Na & H+** -> **R-C≡C-H** - **R-C≡CH & OH-** -> **(R-C≡C-)2** ### Carboxylic Acids and Derivatives - **H3O+** -> **R-OH** - **LiAlH4** -> **R-NH2** - **Br2, NaOH** -> **R-NH2** ### Alkynes - **NaNH2 or NaH** -> **R-C≡C-Na+** - **R-Na & H+** -> **R-C≡C-H** - **R-C≡C-H & OH-** -> **(R-C≡C-)2** ### Alkenes - **H2, Pd, Pt, Raney Ni** -> **R** - **Br2** -> **Br** - **MCPBA or RCO3H, CH2Cl2** -> **R** - **H2O2** -> **R** - **OSO4, H2O2 or KMnO4, cold dilute** -> **R** - **HIO4** -> **R** - **O3, (CH3)2S** -> **R** - **KMnO4, H3O+** -> **R** - **Br2, H2O** -> **R** - **Na, NH3** -> **R** - **H2, Lindlar's** -> **R** - **DIBAL-H, -78 °C** -> **R** ### Aromatic Reactions - **Cl2, AICI3 or FeCl3** -> **Cl** - **Br2, FeBr3** -> **Br** - **CH3CI, AICI3** -> **CH3** - **CO, HCI, AICI3, CuCl** -> **H** - **HCI, Zn(Hg) or HNNH, NaOH, Δ** -> **R** - **KMnO4, H3O+ or Na2Cr2O7, H2SO4** -> **OH** - **HNO3, H2SO4** -> **NO2** - **H2, Pd, Pt, or Raney Ni** -> **NH2** - **HCl(aq), Zn, Sn, or Fe** -> **NH2** - **SO3, H2SO4, Δ** -> **SO3H** - **H2O, H2SO4** -> **SO3H** ### Nitrile Reactions - **1. NaOH, 2. RX** -> **R** - **NaNO2, HCI** -> **N≡N CF** - **CuCI (Br)** -> **CI (Br)** - **CuCN** -> **CN** - **KBF4 or KI** -> **F (I)** - **H3PO2** -> **-** - **H3O+** -> **OH**
