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GENERIC NAME fentanyl TRADE, BRAND, OR PROPRIETARY NAMES • Duragesic® • Sublimaze® CLASSES • Narcotic analgesic • Narcotic agonist STANDARD SUPPLIES • Ampule • Vial MECHANISMS OF ACTION • Alleviates pain by depressing the central nervous system • Depresses respiratory centers in the brainstem • De...

GENERIC NAME fentanyl TRADE, BRAND, OR PROPRIETARY NAMES • Duragesic® • Sublimaze® CLASSES • Narcotic analgesic • Narcotic agonist STANDARD SUPPLIES • Ampule • Vial MECHANISMS OF ACTION • Alleviates pain by depressing the central nervous system • Depresses respiratory centers in the brainstem • Decreases venous return to the heart • Decreases preload • Decreases afterload INDICATION • Pain management CONTRAINDICATIONS • Known hypersensitivity to the drug • Head injury • Decreased level of consciousness • Respiratory depression • Hemodynamically significant hypotension FENTANYL 1 ADVERSE REACTIONS/SIDE EFFECTS • Central nervous system depression • Respiratory depression • Respiratory arrest • Hypotension • Bradycardia • Tachycardia • Dysrhythmias • Syncope • Dyspnea • Nausea • Vomiting ROUTES OF ADMINISTRATION • IV • IO • IM ONSET OF ACTION • 1 to 3 minutes ADULT DOSAGES • 25 to 50 mcg • Maximum dosage 200 mcg PEDIATRIC DOSAGES • 1.0 to 2.0 mcg/kg • Maximum dosage 50 mcg SPECIAL CONSIDERATIONS • Peak effect of the drug is 3 to 5 minutes • Duration of the drug is 30 to 60 minutes • Fentanyl 100 mcg is equivalent in analgesia to morphine10 mg FENTANYL 2

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