Type II Diabetes Past Paper PDF
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University of Michigan-Flint
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This document includes questions about Type II diabetes, Metformin, and SGLT2 Inhibitors. It may be part of a medical exam or study materials.
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15. What lifestyle factors are associated with Type II diabetes? a. Diabetes self-management, education, support, avoidance of clinical inertia, and social determinants of health b. Established/high-risk atherosclerotic CV disease/HF/CKD i. Include a...
15. What lifestyle factors are associated with Type II diabetes? a. Diabetes self-management, education, support, avoidance of clinical inertia, and social determinants of health b. Established/high-risk atherosclerotic CV disease/HF/CKD i. Include agents that reduce cardiorenal risk c. Pharmacologic approaches i. Adequate e icacy ii. Maintain treatment goals d. Weight management 16. MOA of metformin Decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity (increases peripheral glucose uptake and utilization) 17. Metformin severe ADE i. GI NVD, flatulence, dyspepsia, abdominal pain (rapid dose escalation, IR formulation, chronic asymptomatic gastritis) ii. Lactic acidosis (increases with increased serum levels, kidney impairment, hepatic impairment, decreased tissue perfusion, >65 y/o, contrast, excess alcohol, hypoxic states) iii. Vitamin B12 deficiency interferes with absorption of B12 (duration of therapy, higher dosages, inadequate B12 stores, >65 y/o 18. Metformin contraindications? Several drug interactions, severe renal impairment (CrCl
