Embryology 7 Disorders in Tooth Form and Function - 2.5 PDF
Document Details
Uploaded by InnocuousSilver3002
University of Plymouth
Tags
Summary
This document discusses the embryology of tooth formation, including disorders in tooth form and function. It explores the role of genes, like MSX1 and PAX9, and developmental processes. The document also covers tooth renewal mechanisms in various species.
Full Transcript
**[Embryology 7 disorders in tooth form and function - 2.5]** Deep palatal groove - groove from root to crown Most common hypodontial teeth - - Transposition - lateral incisor and canine switch positions Velopharyngeal insufficiency (VP) = common in children with a history of cleft palate...
**[Embryology 7 disorders in tooth form and function - 2.5]** Deep palatal groove - groove from root to crown Most common hypodontial teeth - - Transposition - lateral incisor and canine switch positions Velopharyngeal insufficiency (VP) = common in children with a history of cleft palate - Main causes of disturbed tooth development - - - - **[Genes]** MSX1 = early craniofacial development - - PAX9 = tooth development (in particular formation of molars) - AXIN2 EDA WNT10A DLX genes BMP4 ![](media/image6.png) **Tooth renewal** Mouse = monophyodont Humans = diphyodont - fragmentation of dental lamina after initiation of the replacement tooth Reptiles = polyphyodont Humans have only two dentitions due to: 1. 2. - 3. - ![](media/image3.png) ![](media/image2.png)