Podcast
Questions and Answers
What genetic factor is primarily associated with the development of molars?
What genetic factor is primarily associated with the development of molars?
Which condition is commonly associated with children having a history of cleft palate?
Which condition is commonly associated with children having a history of cleft palate?
What is the main reason humans experience only two dentitions during their lifetime?
What is the main reason humans experience only two dentitions during their lifetime?
What type of tooth replacement do humans undergo compared to other species?
What type of tooth replacement do humans undergo compared to other species?
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Which gene is NOT listed as a cause of disturbed tooth development?
Which gene is NOT listed as a cause of disturbed tooth development?
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Which gene is primarily associated with early craniofacial development?
Which gene is primarily associated with early craniofacial development?
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What characteristic distinguishes humans as diphyodonts compared to other tooth types?
What characteristic distinguishes humans as diphyodonts compared to other tooth types?
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In tooth form and function disorders, which phenomenon describes the switching of lateral incisor and canine positions?
In tooth form and function disorders, which phenomenon describes the switching of lateral incisor and canine positions?
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Which of the following genes does NOT directly relate to tooth development?
Which of the following genes does NOT directly relate to tooth development?
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Which condition is characterized by a failure in the velopharyngeal closure and is common in specific populations?
Which condition is characterized by a failure in the velopharyngeal closure and is common in specific populations?
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Study Notes
Embryology of Tooth Disorders
- Tooth development has seven types of disorders.
- Non-invasive restorations include Glass ionomer cement and Composite.
- Conventional restorations include Composite and CAD/CAM ceramics.
- Tooth disintegration with defects (small to medium) can be treated with tooth cleaning, and GIC application.
- Disintegration with larger defects needs cavity preparation, total etch, composite application and can sometimes require CAD/CAM ceramic crown.
- Extensive disintegration with dentine exposure requires local or general anesthesia and CAD/CAM ceramic crown insertion with composite cement.
Deep Palatal Groove
- The deep palatal groove extends from the root to the crown.
- Uppers: Lateral incisors are most commonly affected.
- Lowers: Central incisors are most commonly affected.
Transposition and Velopharyngeal Insufficiency
- Tooth transposition: Lateral incisors and canines switch positions.
- Velopharyngeal insufficiency (VP): Common in children with cleft palate.
- The condition leads to hypernasality and speech difficulties.
Main Causes of Disturbed Tooth Development
- Gene mutations cause hereditary disturbances.
- Epithelial-mesenchymal interactions are disrupted.
- Trauma and infection contribute to the issue.
- MSX1 is involved in early craniofacial development.
Tooth Morphogenesis
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Mutations in PAX9 cause issues in molar formation.
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Mutations in AXIN2, EDA,WNT10A, DLX and BMP4 genes cause tooth development problems. Specific mutations affect molar development.
Tooth Renewal
- Mouse teeth are monophyodont.
- Human teeth are diphyodont (two sets of teeth).
- Tooth renewal mechanisms vary in reptiles (polyphyodont).
- Human tooth development is due to evolution and functional adaptation.
- Genes like MSX1 and PAX9 contribute to the differences between human dentition.
- RUNX2 limits tooth replacement.
Evolutionary Gene Silencing and Dental Lamina
- Dental lamina activity varies between mammals and reptiles.
- Reptiles have active dental lamina throughout life.
- Humans develop primary and secondary teeth early in gestation.
- Dental lamina regresses after permanent teeth development.
Tooth Anomalies
- Anomalies include tooth number, shape, size, structure, eruption (problems with eruption/tooth eruption).
- Other anomalies include root issues/anomalies.
- Genetic influences, disruptions in development, and trauma result in dental anomalies.
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Description
Test your knowledge on the embryology of tooth disorders, including types of disorders, treatment options, and specific structural anomalies. Explore conditions like deep palatal groove and tooth transposition. This quiz covers fundamental concepts that are essential for dental professionals.
