Drug-of-Choice-DOC PDF
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This document provides a list of drugs and their corresponding indications for various medical conditions. It's likely a reference guide for healthcare professionals.
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DRUG OF CHOICE ANTIBACTERIALS CELL WALL SYNTHESIS INHIBITORS DOC for Gas Gangrene aka Clostridial myonecrosis Pen...
DRUG OF CHOICE ANTIBACTERIALS CELL WALL SYNTHESIS INHIBITORS DOC for Gas Gangrene aka Clostridial myonecrosis Penicillin G DOC for Neisseria meningitidis DOC for Pasteurella multocida Penicillin V DOC for Lyme disease DOC for Syphilis Benzathine Penicillin DOC for Rheumatic heart disease Methicillin DOC for Penicillin Resistant Staphylococcus aureus Ampicillin + Gentamicin DOC for Listeriosis Cefazolin DOC for Surgical prophylaxis Ceftriaxone (IM) + Azithromycin (Oral): DOC for Gonorrhea Ceftriaxone (Rocephin®) DOC for Meningitis (CHILDREN) cause by Haemophilus influenzae Cefuroxime DOC for Community Acquired Pneumonia Vancomycin DOC for Methicillin Resistant Staphylococcus aureus Vancomycin (US) DOC for Pseudomembranous colitis Metronidazole (PHL) PROTEIN SYNTHESIS INHIBITORS Streptomycin DOC for Tularemia aka Rabbit fever DOC for Chlamydia Tetracycline DOC for Rickettsia DOC for Mycoplasma DOC for Cholera (Rice watery diarrhea) DOC for Leptospirosis Doxycycline DOC for Q Fever DOC for Lymphogranuloma venereum Demeclocycline DOC for SIADH Old: Chloramphenicol DOC for Typhoid fever New: Ciprofloxacin, Ceftriaxone DOC for Diphtheria Erythromycin (llosone®) DOC for Pertussis DOC for Legionnaire's disease Linezolid (Zyvox®) DOC for Vancomycin Resistant Staphylococcus aureus Streptogramins Treatment for Linezolid resistant Staphylococcus aureus NUCLEIC ACID TRANSCRIPTION & REPLICATION INHIBITORS Ag Sulfadiazine (Flammazine®) DOC for Burns DOC for Pneumocystis carinii/ jirovecii pneumonia (PCP) - Pneumonia in AIDS patient Co-trimoxazole (SMX + TMP) DOC Uncomplicated UTI Sulfadiazine + Pyrimethamine DOC for Toxoplasmosis Sulfadoxine + Pyrimethamine (Fansidar®) Chloroquine resistant malaria DOC for Anthrax Ciprofloxacin Malignant external otitis (MEO) DOC for Complicated UTI Mupirocin DOC for Impetigo Rifampicin DOC for Prophylaxis of close contacts of meningococcal and Haemophilus meningitis ANTI-LEPROSY DRUG Dapsone DOC for Leprosy aka Hansen’s Disease ANTIPROTOZOALS DOC for Pseudomembranous colitis DOC for Trichomoniasis DOC for Amebiasis Metronidazole (Flagyl®) DOC for Giardiasis DOC for Anaerobes DOC for Tetanus Iodoquinol DOC for Asymptomatic amebiasis Na Stibogluconate DOC for Leishmaniasis Nifurtimox DOC for American Trypanosomiasis or Chaga's disease Suramin DOC for African trypanosomiasis Melarsoprol DOC for Meningoencephalitic ASS ANTHELMINTICS PLATYHELMINTHS/FLATWORMS New: Triclabendazole DOC for Sheep liver fluke (Fascioliasis) DOC for Cestode (Tapeworm) Praziquantel DOC for Trematode (Blood Fluke: Schistosomiasis) NEMATODES DOC for Nematodes DOC for Ascariasis (Roundworm) Mebendazole DOC for Trichuriasis (Whipworm) DOC for Ancylostomiasis (Hookworm) Pyrantel Pamoate DOC for Enterobiasis (Pinworm) Thiabendazole DOC for Strongyloidiasis (Threadworm) Ivermectin DOC for Onchocerciasis (River blindness) Diethylcarbamazine (DEC) DOC for Filariasis (Elephantiasis) ANTIMALARIALS DOC for Malaria Chloroquine (Aralen®) Erythrocytic form of Malaria Exoerythrocytic form of Malaria Primaquine Radical cure of Malaria Quinine Drug resistant of Malaria ANTIFUNGALS TRIAZOLE ANTIFUNGALS Itraconazole DOC for Sporotrichosis aka Rose Gardener's Disease Fluconazole (Diflucan®) - IV DOC for Fungal (Cryptococcal) meningitis aka Pigeon droppings POLYENE ANTIFUNGALS Amphotericin B (Fungizone®) DOC for Systemic fungal infections Nystatin (Mycostatin®) DOC for Candidiasis Natamycin (Natacyn®) DOC for Fungal conjunctivitis ECHINOCANDINS Caspofungin DOC for Aspergillosis Griseofulvin DOC for Ringworm infections ANTIVIRALS DOC for Herpes simplex virus (Genital herpes) Acyclovir (Zovirax®) DOC for Herpes zoster (Chicken pox, Shingles) Entecavir DOC for Hepatitis B, C, D Oseltamivir DOC for Severe influenza infection Ganciclovir DOC for Cyclomegavirus Antiretrovirals DOC for AIDS (Last stage of HIV) SCABICIDES AND PEDICULICIDES Permethrin (Kwell®) DOC for Scabies ANTICANCER Mitotane DOC for Adrenocortical cancer Busulfan DOC for Chronic myelogenous leukemia Chlorambucil + Rituximab DOC for Chronic lymphocytic leukemia Bleomycin DOC for Metastatic testicular cancer Irinotecan DOC for Metastatic colon cancer Gemcitabine DOC for Pancreatic cancer Pipobroman DOC for Polycythemia vera Tamoxifen DOC for Breast cancer (Premenopausal) Anastrozole DOC for Breast cancer (Postmenopausal) Filgrastim (G-CSF) Neutropenia in cancer patient Oprelvekin (IL-11) Thrombocytopenia in cancer patient OCP + NSAIDs DOC for Endometriosis Medroxyprogesterone DOC for Endometrial cancer Cisplatin if localized; Carboplatin if metastatic DOC for Cervical cancer Etoposide DOC for Small cell lung cancer Flutamide DOC for Prostate cancer Plicamycin aka Mithramycin DOC for Cancer-related hypercalcemia CNS STIMULANTS Caffeine (1,3,7-trimethylxanthine) DOC as CNS Stimulant Methylphenidate (Ritalin®) DOC for ADHD AUTONOMIC NERVOUS SYSTEM Epinephrine DOC for Anaphylactic shock Norepinephrine DOC for Septic shock Dobutamine DOC for Cardiogenic shock Neostigmine DOC for Myasthenia gravis Modafinil DOC for Narcolepsy Phenoxybenzamine DOC for Pheochromocytoma Atropine DOC for Physostigmine toxicity and Organophosphate poisoning CENTRAL NERVOUS SYSTEM Old: Lorazepam (Atevan®) DOC for Status epilepticus New: Midazolam Phenobarbital DOC for Neonatal (Febrile) seizure Vigabatrin DOC for Infantile spasm Zaleplon (or Ramelteon) DOC for Insomnia (Difficulty falling asleep) Zolpidem (or Eszopiclone) DOC for Insomnia (Difficulty falling asleep and staying asleep) DOC for Tic douloureux aka Trigeminal neuralgia Carbamazepine DOC for Focal (Partial) seizure DOC for Tonic-Clonic Seizure Valproic acid DOC for Atonic Seizure DOC for Absence seizure (Adult) Ethosuximide DOC for Absence seizure (Children) Chlorpromazine DOC for Hiccups Clozapine DOC for Resistant schizophrenia Risperidone First agent for Schizophrenia Cyproheptadine DOC for Serotonin Syndrome DOC for Depression DOC for Anxiety Fluoxetine DOC for Obsessive-compulsive disorder (OCD) DOC for Bulimia Venlafaxine Depression + Anxiety Duloxetine Depression + Anxiety + Pain License Depression + Anxiety + Pain this review season Milnacipran Fibromyalgia Lithium carbonate DOC for Bipolar disorder Levodopa DOC for Parkinson’s disease Selegiline On-off of Parkinson's disease Tolcapone Wear-off of Parkinson's disease CARDIOVASCULAR SYSTEM Acetazolamide DOC for Glaucoma ACEls DOC for Congestive Heart Failure Nimodipine DOC for Subarachnoid hemorrhage Diazoxide DOC for Insulinoma Nitroprusside DOC for Hypertensive crisis Clonidine DOC for Hypertensive urgency Methyldopa DOC for Gestational hypertension Beta Blockers/CCBs/Nitrates/ DOC for (Chronic) Stable angina Aspirin + Clopidogrel DOC for Unstable angina CCBs: Nifedipine DOC for Prinzmetal (Vasospastic) angina Ranolazine DOC for Chronic stable angina + Bradycardia (Hypotension) Statin DOC for Hypercholesterolemia Fibrates DOC for Hypertriglyceridemia DOC for Acute supraventricular tachycardia aka Adenosine Paroxysmal supraventricular tachycardia (PSVT) Amiodarone DOC for Ventricular tachycardia (fibrillation) DOC for Torsade's de Pointes Magnesium sulfate DOC for Eclampsia ENDOCRINE SYSTEM DOC for Central Diabetes Insipidus Desmopressin DOC for Nocturnal enuresis Hydrochlorothiazide DOC for Nephrogenic Diabetes Insipidus DOC for Type 1 Diabetes Mellitus aka Insulin Dependent Diabetes Mellitus Insulin DOC for Gestational Diabetes Mellitus Metformin DOC for Type 2 Diabetes Mellitus aka Non-Insulin Dependent Diabetes Mellitus Mecasermin For Dwarfism Octreotide DOC for Acromegaly Oxytocin DOC for Labor Hydrocortisone DOC for Addison’s Disease Spironolactone DOC for Conn’s Disease aka Hyperaldosteronism Betamethasone DOC for Respiratory Distress Syndrome Corticosteroid DOC for Sarcoidosis DOC for Infantile Hypothyroidism aka Creatinism Levothyroxine DOC for Myxedema DOC for Hashimoto’s disease (Autoimmune thyroiditis) Methimazole DOC for Hyperthyroidism Propylthiouracil (PTU) DOC for Hyperthyroidism (Pregnant) Calcium DOC for Hyperphosphatemia Finasteride DOC for of BPH GASTROINTESTINAL TRACT Glucocorticoids DOC for Crohn’s Disease Mesalazine (aka Mesalamine) DOC for Ulcerative colitis DOC for Peptic Ulcer Disease PPI DOC for Zollinger-Ellison Syndrome DOC for GERD Loperamide DOC for Diarrhea Bismuth subsalicylate DOC for Infectious Diarrhea OTHERS Methotrexate DOC for Rheumatoid Arthritis NSAIDs DOC for Osteoarthritis Bisphosphonates DOC for Osteoporosis NSAIDs, Colchicine DOC for Acute gout Allopurinol (with Colchicine) DOC for Chronic gout (+ Kidney disease) Lactulose DOC for Hepatic encephalopathy Alprostadil DOC for Patent Ductus Arteriosus (PDA) open Ibuprofen DOC for Patent Ductus Arteriosus (PDA) closure Indomethacin Diphenhydramine (Benadryl AH®) DOC for Acute dystonic crisis or Torticollis (Neck twisting) Sodium bicarbonate DOC for Metabolic acidosis Sodium/Ammonium/Calcium chloride DOC for Metabolic alkalosis Potassium Iodide DOC for Cutaneous lymphatic sporotrichosis Doxylamine + Pyridoxine DOC for Motion sickness in Pregnant women Naproxen DOC for Fever of Malignancy Dantrolene DOC for Malignant Hyperthermia Dexmedetomidine Analgesic + Sedative Reserpine Antihypertensive + Psychotherapeutic (Anxiety) Lidocaine Local Anesthetic + Anti-Arrhythmia Phenytoin Anti-Seizure + Anti-Arrhythmia Diazepam Anti-Seizure + Spasmolytic Bupropion Anti-Depressant + Smoking Deterrent Amantadine Anti-Viral + Anti-Parkinson Vidarabine Anti-Viral + Anti-Cancer Drug (Leukemia) Quinidine Antimalaria + Anti-Arrhythmia Magnesium Sulfate Anticonvulsant + Anti-Arrhythmia Ketoconazole Antifungal + Anti Cushing Syndrome Misoprostol Antisecretory + Cytoprotectant Promethazine Antipsychotic + Antihistaminic + Antiemetic Hydroxychloroquine DMARD + Anti-Malarial Drug Penicillamine DMARD + Drug for Wilson's Disease Methotrexate DMARD + Anti-Cancer Drug Tocilizumab DMARD + Anti-COVID