Antibacterials and Their Uses

Antibacterials

• Penicillin G is the drug of choice for Gas Gangrene, Neisseria meningitidis, Pasteurella multocida, Lyme Disease, and Syphilis.
• Penicillin V is the drug of choice for Rheumatic Heart Disease.
• Methicillin is the drug of choice for penicillin-resistant Staphylococcus aureus.
• Ampicillin + Gentamicin is the drug of choice for Listeriosis.
• Cefazolin is the drug of choice for surgical prophylaxis.
• Ceftriaxone (IM) + Azithromycin (Oral) is the drug of choice for Gonorrhea.
• Ceftriaxone (Rocephin®) is the drug of choice for Meningitis (children) caused by Haemophilus influenzae.
• Cefuroxime is the drug of choice for Community Acquired Pneumonia.
• Vancomycin is the drug of choice for Methicillin Resistant Staphylococcus aureus and Pseudomembranous Colitis.
• Metronidazole (PHL) is the drug of choice for Pseudomembranous colitis.
• Streptomycin is the drug of choice for Tularemia and Chlamydia.
• Tetracycline is the drug of choice for Rickettsia, Mycoplasma, Cholera, and Leptospirosis.
• Doxycycline is the drug of choice for Q Fever and Lymphogranuloma venereum.
• Demeclocycline is the drug of choice for Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH).
• Chloramphenicol is the drug of choice for Typhoid Fever and Diphtheria.
• Ciprofloxacin & Ceftriaxone are new drugs of choice for Typhoid Fever.
• Erythromycin (llosone®) is the drug of choice for Pertussis and Legionnaire’s Disease.
• Linezolid (Zyvox®) is the drug of choice for Vancomycin Resistant Staphylococcus aureus.
• Streptogramins are used to treat Linezolid-resistant Staphylococcus aureus.
• Ag Sulfadiazine (Flammazine®) is the drug of choice for burns.
• Co-trimoxazole (SMX + TMP) is the drug of choice for Pneumocystis carinii/ jirovecii pneumonia and uncomplicated UTIs.
• Sulfadiazine + Pyrimethamine is the drug of choice for Toxoplasmosis.
• Sulfadoxine + Pyrimethamine (Fansidar®) is the drug of choice for Chloroquine-resistant Malaria.
• Ciprofloxacin is the drug of choice for Anthrax, malignant external otitis, and complicated UTIs.
• Mupirocin is the drug of choice for Impetigo.
• Rifampicin is the drug of choice for prophylaxis of close contacts of meningococcal and Haemophilus meningitis.
• Dapsone is the drug of choice for Leprosy (Hansen’s Disease).

Antimalarials

• Chloroquine (Aralen®) is the drug of choice for Malaria.
• Primaquine is the drug of choice for the radical cure of Malaria.
• Quinine is the drug of choice for drug-resistant Malaria.

Antiprotozoals

• Metronidazole (Flagyl®) is the drug of choice for Pseudomembranous colitis, Trichomoniasis, Amebiasis, Giardiasis, and Anaerobes.
• Iodoquinol is the drug of choice for Asymptomatic Amebiasis.
• Na Stibogluconate is the drug of choice for Leishmaniasis.
• Nifurtimox is the drug of choice for American Trypanosomiasis or Chagas’ Disease.
• Suramin is the drug of choice for African Trypanosomiasis.
• Melarsoprol is the drug of choice for Meningoencephalitic African Trypanosomiasis.

Antifungals

• Itraconazole is the drug of choice for Sporotrichosis.
• Fluconazole (Diflucan®) is the drug of choice for Fungal (Cryptococcal) Meningitis.
• Amphotericin B (Fungizone®) is the drug of choice for Systemic Fungal Infections.
• Nystatin (Mycostatin®) is the drug of choice for Candidiasis.
• Natamycin (Natacyn®) is the drug of choice for Fungal Conjunctivitis.
• Caspofungin is the drug of choice for Aspergillosis.
• Griseofulvin is the drug of choice for Ringworm Infections.

Antivirals

• Acyclovir (Zovirax®) is the drug of choice for Herpes Simplex Virus (Genital Herpes) and Herpes Zoster (Chickenpox, Shingles).
• Entecavir is the drug of choice for Hepatitis B, C, and D.
• Oseltamivir is the drug of choice for Severe Influenza Infection.
• Ganciclovir is the drug of choice for Cytomegalovirus.

Gastrointestinal Tract

• Glucocorticoids are the drug of choice for Crohn’s Disease.
• Mesalazine (Mesalamine) is the drug of choice for Ulcerative Colitis.
• PPIs (Proton Pump Inhibitors) are the drug of choice for Peptic Ulcer Disease and Zollinger Ellison Syndrome

Other Drugs

• Hydrochlorothiazide is the drug of choice for Nephrogenic Diabetes Insipidus.
• Insulin is the drug of choice for Type 1 Diabetes Mellitus.
• Metformin is the drug of choice for Type 2 Diabetes Mellitus.
• Mecasermin is the drug of choice for Dwarfism.
• Octreotide is the drug of choice for Acromegaly.
• Oxytocin is the drug of choice for Labor.
• Hydrocortisone is the drug of choice for Addison’s Disease.
• Spironolactone is the drug of choice for Conn’s Disease (Hyperaldosteronism).
• Betamethasone is the drug of choice for Respiratory Distress Syndrome.
• Corticosteroids are the drug of choice for Sarcoidosis.
• Levothyroxine is the drug of choice for Infantile Hypothyroidism and Myxedema.
• Methimazole and Propylthiouracil (PTU) are the drug of choice for Hyperthyroidism. PTU is the drug of choice during pregnancy.
• Calcium is the drug of choice for Hyperphosphatemia.
• Finasteride is the drug of choice for Benign Prostatic Hyperplasia (BPH).

Anthelmintics

• Triclabendazole is the drug of choice for Sheep Liver Fluke (Fascioliasis) and Cestode (Tapeworm).
• Praziquantel is the drug of choice for Trematode (Blood Fluke: Schistosomiasis).
• Mebendazole is the drug of choice for Ascariasis (Roundworm), Trichuriasis (Whipworm), and Ancylostomiasis (Hookworm).
• Pyrantel Pamoate is the drug of choice for Enterobiasis (Pinworm).
• Thiabendazole is the drug of choice for Strongyloidiasis (Threadworm).
• Ivermectin is the drug of choice for Onchocerciasis (River Blindness).
• Diethylcarbamazine (DEC) is the drug of choice for Filariasis (Elephantiasis).

This quiz explores various antibacterial drugs and their specific medical uses. It covers the drug of choice for several conditions, including infections and prophylaxis. Test your knowledge on which antibacterials are effective against different bacteria.