Diabetes Lecture Notes PDF

Summary

These lecture notes cover the topic of diabetes, including objectives and different treatment options. The notes discuss oral and injectable treatment methods, and provide comparisons between different types of insulin. The document also details the mechanisms of action for some medications.

Full Transcript

PAS 520- PHARMACOLOGY Michelle Boysel, PharmD, RPh Clinical Pharmacist [email protected] Diabetes Mellitus WEE K SE VEN : LECT URE T WO Objectives WEE K SE VEN : LECT URE T WO Chapter Objectives  Describe the various oral treatmen...

PAS 520- PHARMACOLOGY Michelle Boysel, PharmD, RPh Clinical Pharmacist [email protected] Diabetes Mellitus WEE K SE VEN : LECT URE T WO Objectives WEE K SE VEN : LECT URE T WO Chapter Objectives  Describe the various oral treatment options used to treat diabetes mellitus.  Describe the various injectable treatment options used to treat diabetes mellitus.  Compare the different types of insulin used to treat diabetes mellitus. insulin secretes useglucose forenergy gaffinproduce insulinhristant DM1 vs DM2 childrenget Kitsis DM1 vs DM2 DM1 vs DM2 intro 90% of all problems involving the thyroid are due to Biguanides Medications: Metformin MOA: Decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity intokey hole key Effects: ◦ Weight Neutral ◦ Lowers HbA1C 1- 2% largedropin comparison EIest.am Side Effects: Diarrhea, Nausea, Flatulence, Vitamin B12 Deficiency Clinical Pearls: canteadtoanemia ◦ Contraindicated in severe renal dysfunction (eGFR

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