Coordination of Insulin and Glucagon Release in Flies PDF

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Summary

This document details the complementary interactions of glucagon and insulin in regulating blood glucose levels. It presents diagrams and figures illustrating the coordination process in flies and mammalian homologs. The research discussed includes findings from Oh et al., 2019 and Papazoglou et al., 2021.

Full Transcript

혈중 포도당 증가 혈중 포도당 감소 혈중 포도당 정상으로 증가 혈중 포도당 정상으로 감소 FIGURE 7-26 Complementary interactions of glucagon and insulin (글루카곤과 인슐린의 보완적 상호관계) Copyright © 2021 Pearson Education Ltd. All Rights Reserved Coordination of the release of insulin and gluc...

혈중 포도당 증가 혈중 포도당 감소 혈중 포도당 정상으로 증가 혈중 포도당 정상으로 감소 FIGURE 7-26 Complementary interactions of glucagon and insulin (글루카곤과 인슐린의 보완적 상호관계) Copyright © 2021 Pearson Education Ltd. All Rights Reserved Coordination of the release of insulin and glucagon by a single pair of glucose-sensing (CN) neurons in flies Insulin CN neuron Glucagon Ohal., et al., 2019,Nature Nature Oh et 2019, Copyright © 2021 Pearson Education Ltd. All Rights Reserved CN neurons: Coordination of the release of insulin and glucagon by a single pair of glucose-sensing neurons in flies Oh et al., 2019, Nature Copyright © 2021 Pearson Education Ltd. All Rights Reserved Mammalian homolog of CN neurons: PVNOXT neurons? Papazoglou et al., 2021, Cell Metabolism Copyright © 2021 Pearson Education Ltd. All Rights Reserved

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