Summary

This document discusses the glucose metabolism in cancer cells. It examines the differences in how cancer cells use glucose compared to normal cells, and how these differences could be used for diagnosis.

Full Transcript

Glucose convertsto yataitsit.ietitsin pyruvate to 36ATP lowerATP cancercellcanthenuse lactatetoformbiomass incorporation tocell proliferation ...

Glucose convertsto yataitsit.ietitsin pyruvate to 36ATP lowerATP cancercellcanthenuse lactatetoformbiomass incorporation tocell proliferation upstream regulator Ygueht.tn apoptosis ap isserinethreoninekinase downstreameffector positive regulator growthpromoter is keepalive whatever alreadythere overactivation R upstream EEYEExamples Ras can directly activate Pisk Myc heirauman move helpsw overall cell survival growth Att rregulate glucose transporters gaffgtse thannormalcell mutatedP53 increased switchprotein cell criticalmetabolic seption mothstleinthe transports Isabella porters moreforcancerto change howcell usesglucose now its differentin cancerc ells couldworkas a blood marker for diagnosis highly reactive caninteract create DNA damage plowlevelsaregood helpw cellproliferation highlevels

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