Revision on CHO Metabolism PDF
Document Details
Uploaded by SteadfastSmokyQuartz7887
Faculty of Applied Health Science Technology
Tags
Summary
This document provides a revision on carbohydrate metabolism. It covers different types of metabolic pathways such as anabolic, catabolic, and amphibolic pathways including key enzymes. It also describes various processes like glycolysis, Krebs cycle, and the HMP shunt and relates them to other processes.
Full Transcript
# Revision on CHO Metabolism 1. A pure anabolic pathway is: - Glycogenesis - Gluconeogenesis 2. A pure catabolic pathway is: - Glycolysis - Oxidative decarboxylation - Krebs cycle - HMP shunt - Uronic acid pathway - Glycogenolysis 3. Amphibolic pathway is Krebs cycle 4. Aerobic g...
# Revision on CHO Metabolism 1. A pure anabolic pathway is: - Glycogenesis - Gluconeogenesis 2. A pure catabolic pathway is: - Glycolysis - Oxidative decarboxylation - Krebs cycle - HMP shunt - Uronic acid pathway - Glycogenolysis 3. Amphibolic pathway is Krebs cycle 4. Aerobic glycolysis of glucose gives 6-8 ATP - Anaerobic glycolysis of glucose gives 2 ATP - Complete oxidation of one molecule of glucose aerobically gives 36-38 ATP - Oxidative decarboxylation of 2 molecules of pyruvate gives 6 ATP - Oxidation of one molecule of acetyl CoA by Krebs gives 12 ATP 5. Examples of substrate level phosphorylation include: - In glycolysis 2 examples (by phosphoglycerate kinase and pyruvate kinase) - In Krebs cycle (by succinate thiokinase) 6. A coenzyme required by: - HMP shunt is NADP - Glyceraldhyde-3-phosphate DH is NAD - Succinate DH is FAD 7. Uronic acid pathway is important for production of Glucuronic acid in the form of UDP-glucuronic acid (used for detoxification reactions - Conjugation reactions - Synthesis of vitamin C in animals not in humans) 8. HMP shunt is important in production of NADPH+H and ribose-5-phosphate. 9. The key enzymes of: - Glycolysis (Hexokinase and glucokinase - Phosphofructokinasel - Pyruvate kinase) - Krebs (citrate synthase - Isocitrate synthase - a ketoglutarate DH) - HMP shunt (Glucose-6-phosphate DH) - Glycogenesis (Glycogen synthase) - Glycogenolysis (Glycogen phosphorylase) - Gluconeogenesis (Pyruvate carboxylase - Phosphoenol pyruvate carboxykinase - Fructose 1, 6 biphosphatase - Glucos-6-phosphatase)
