BPS337 Exam 4 to Final Quizzes PDF

BPS337 Exam 4 to Final Quizzes -- Clements and ANS **Question 1 **(1 point) What receptors/signals are used in the SNS? Question 1 options: nAchR preganglion and Acetylcholine post -- ----------------------------------------------- nAchR  preganglion and mAchR post **nAchR prega...

BPS337 Exam 4 to Final Quizzes -- Clements and ANS **Question 1 **(1 point) What receptors/signals are used in the SNS? Question 1 options: nAchR preganglion and Acetylcholine post -- ----------------------------------------------- nAchR  preganglion and mAchR post **nAchR preganglion and norepinephrine post** mAchR preganglion and norepinephrine post **Question 2 **(1 point)   [**Listen**](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_1) An increase in blood pressure will? Question 2 options: increase RAAS signaling -- ---------------------------------------------- **increase PNS activation and decrease SNS** increase SNS activation  and decrease PNS decrease natriuretic peptides **Question 3 **(1 point)   [**Listen**](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_1) **Acetylcholine** receptors on the **endothelium** cause: Question 3 options: **vasodilation via NO signals** -- --------------------------------------------- increased nerve transmission in the vagus activation of PKA in the heart vasoconstriction due to MLC phosphorylation **Question 4 **(1 point)   [**Listen**](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_1) **ADH** directly activates: Question 4 options: MR to produce ENaC -- ------------------------------------------------------------- renin release by juxtaglomerular cells **V2 receptors to increase H~2~O absorption in the kidney** **Question 5 **(1 point) Which **two** **proteins** are responsible for **release/reuptake of Ca^++^ from/to the sarcoplasmic reticulum in cardiomyocytes**: Question 5 options: **Release: Ryanodine receptor. Reuptake: SERCA.** -- ------------------------------------------------------------------- Release: Vasopressin. Reuptake:  Myosin. Release: Troponin C. Reuptake:  Phosphodiesterase 3. Release: myosin light chain kinase. Reuptake: myosin phosphatase.   **Question 6.** Vascular resistance is inversely proportional to the: Question 6 options: **radius to the 4^th^ power** -- ------------------------------- blood viscosity radius to the 2^nd^ power Pressure **Question 7 **(1 point)   [**Listen**](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_1) Which is NOT directly increased with SNS activity? Question 7 options: **ANP** -- ---------------- Aldosterone Angiotensin II ADH **Question 8 **(1 point)   [**Listen**](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_1) Natriuretic peptides exert intracellular effects through: Question 8 options: cAMP production -- --------------------- **cGMP production** PDE3 inhibition NO production **Question 9 **(1 point)   [**Listen**](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_1) Increased cardiac contractility will: Question 9 options: decrease O~2~ consumption -- ----------------------------- decrease cardiac output cause vasoconstriction **increase cardiac output** **Question 10 **(1 point)   [**Listen**](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_1) Hydralazine MAY work to reduce blood pressure via what mechanism?  Question 10 options: **Decrease ROS** -- --------------------------- **Acvtivate K+ channels** **Inhibit IP3 receptor** **All of these** Last quiz Question 1 (1 point)    *Saved* [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_1) **M3-AchR activation on lung bronchial smooth muscle:** Question 1 options: Causes bronchoconstriction -- ---------------------------------------------------------------- Causes bronchodilation Increases HR via SNS activity Drives negative feedback in the lung at parasympatheic ganglia Question 2 (1 point)    *Saved* [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_2) On vascular smooth muscle , if both alpha 1 and beta 2 adrenergics are activated, who wins?  Question 2 options: alpha 1 adrenergic signals to cause vasoconstriction -- ------------------------------------------------------ beta 2 adrenergic signals to cause vasodilation Question 3 (1 point)    *Saved* [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_3) Succinylcholine which activates nAchR, has what major physiologic effect?  Question 3 options: increases muscle activity -- ------------------------------------------------------------------------------------ quickly activates, but then desensitizes nAchR signaling to reduce muscle activity Increases Cl- conductance of GABA-A receptors Question 4 (1 point)    *Saved* [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_4) Non-depolarizing neuromuscular junction blockers:  Question 4 options: overactivate nAchR on skeletal muscle to reduce subsequent signals -- -------------------------------------------------------------------- act as competitive antagonists of nAchR act as irreversible nAchR inhibitors have increased blocking activity when combined with sugamaddex Question 5 (1 point)    *Saved* [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_5) Baclofen: Question 5 options: **a GABA-B agonist that hyperpolarizes cells and reduces excitatory signals** -- ------------------------------------------------------------------------------- a GABA-B antagonist that hyperpolarizes cells and reduces excitatory signals **Reduces Ca++ influx** Increases Ca++ influx A and C B and D Question 6 (1 point)    *Saved* [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_6) **Milrinone**:  Question 6 options: **increase cAMP in the heart and increase contractility** -- ----------------------------------------------------------- **inhibits PDE3** decreases cAMP in vessels to increase dilation Increases vasodilation through increases in cGMP **A and B** All of the above Question 7 (1 point)    *Saved* [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_7) **PKA increases cardiac contractility via** Question 7 options: **Coordinated response to increase Ca++ cycling : RyR2, LTCC and PLB phosphorylation** -- ---------------------------------------------------------------------------------------- Increasing MLC phosphorylation via MLCK Direct phosphorylation of cardiac TnC Blocking PDE3 activity Question 8 (1 point)    *Saved* [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_8) Which is in the correct order (highest to least) for **Alpha1 adrenergic receptor affinity** ? Question 8 options: epinephrine, dopamine, phenylephrine, dobutamine -- -------------------------------------------------------- dobutamine, epinephrine, phenylephrine, norepinephrine phenylephrine, norepinephrine, epinephrine, dopamine dopamine, phenylephrine, epinephrine, norepenephrine Question 9 (1 point)    *Saved* [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_9) **Active PKG in vessels**: Question 9 options: **reduces MLC phosphorylation by activating myosin phosphatase and K+ channels and reducing Ca++ channel activities** -- ----------------------------------------------------------------------------------------------------------------------- blocks vascular PKA activity to cause vasodilation increases MLC phosphorylation to cause NO-dependent vasodilation  increase cGMP to cause vasodilation  Question 10 (1 point) [Listen](https://app.readspeaker.com/cgi-bin/rsent?customerid=12292&url=https%3A%2F%2Fbrightspace.uri.edu%2Fd2l%2Flms%2Fquizzing%2Fuser%2Fattempt%2Fquiz_attempt_page_auto.d2l&lang=en_us&readid=d2l_read_element_10) Activation of beta 2- adrenergic receptor:  Question 10 options: **increases vasodilation and bronchodilation via PKA activity** -- --------------------------------------------------------------------------- decreases vasodilation and bronchodilation via PKA activity increases vasoconstriction and bronchodilation via PKG activity increases vasodilation and increases bronchoconstriction via PKA activity