Physiology of the Autonomic Nervous System
26 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the effect of active PKG in blood vessels?

  • Increases cGMP to cause vasodilation
  • Increases MLC phosphorylation to cause NO-dependent vasodilation
  • Blocks vascular PKA activity to cause vasodilation
  • Reduces MLC phosphorylation by activating myosin phosphatase and K+ channels and reducing Ca++ channel activities (correct)

    • Which response is correct regarding the activation of beta 2-adrenergic receptors?

  • Decreases vasodilation and bronchodilation via PKA activity
  • Increases vasodilation and bronchodilation via PKA activity (correct)
  • Increases vasodilation and increases bronchoconstriction via PKA activity
  • Increases vasoconstriction and bronchodilation via PKG activity

    • Which of the following compounds is primarily associated with the increase of MLC phosphorylation?

  • Dopamine
  • Norepinephrine (correct)
  • Dobutamine
  • Epinephrine

    • What is a primary mechanism by which epinephrine affects blood vessels?

    <p>Increases both vasodilation and vasoconstriction through beta and alpha receptors</p> Signup and view all the answers

    How does phenylephrine primarily affect vascular smooth muscle?

    <p>Increases intracellular calcium levels to induce contraction</p> Signup and view all the answers

    What receptors are utilized in the sympathetic nervous system for signaling?

    <p>nAchR preganglion and norepinephrine post</p> Signup and view all the answers

    How does an increase in blood pressure affect the autonomic nervous system?

    <p>Increase PNS activation and decrease SNS</p> Signup and view all the answers

    What effect do acetylcholine receptors on the endothelium have?

    <p>Vasodilation via NO signals</p> Signup and view all the answers

    Which receptors does ADH directly activate to influence kidney function?

    <p>V2 receptors to increase H2O absorption in the kidney</p> Signup and view all the answers

    Which proteins are crucial for the release and reuptake of Ca²⁺ from the sarcoplasmic reticulum in cardiomyocytes?

    <p>Release: Ryanodine receptor. Reuptake: SERCA</p> Signup and view all the answers

    What happens to sympathetically mediated responses when blood pressure increases?

    <p>SNS activation decreases and PNS activation increases</p> Signup and view all the answers

    The activation of V2 receptors by ADH primarily leads to which of the following effects in the kidney?

    <p>Increased water absorption</p> Signup and view all the answers

    What is a consequence of acetylcholine receptor activation on the endothelium?

    <p>Vasodilation due to NO production</p> Signup and view all the answers

    What does vascular resistance depend on?

    <p>Radius to the 4th power</p> Signup and view all the answers

    Which substance is not directly increased by SNS activity?

    <p>ANP</p> Signup and view all the answers

    What mechanism do natriuretic peptides use to exert intracellular effects?

    <p>cGMP production</p> Signup and view all the answers

    What is the effect of increased cardiac contractility?

    <p>Increased cardiac output</p> Signup and view all the answers

    What potential mechanism does Hydralazine use to reduce blood pressure?

    <p>All of these</p> Signup and view all the answers

    What is the physiological effect of M3-AchR activation on bronchial smooth muscle?

    <p>Causes bronchoconstriction</p> Signup and view all the answers

    If both alpha 1 and beta 2 adrenergics are activated in vascular smooth muscle, which effect prevails?

    <p>Vasoconstriction due to alpha 1 activity</p> Signup and view all the answers

    What major physiological effect does succinylcholine have?

    <p>Decreases muscle activity through desensitization</p> Signup and view all the answers

    Non-depolarizing neuromuscular junction blockers primarily act as:

    <p>Competitive antagonists of nAchR</p> Signup and view all the answers

    What is one action of baclofen?

    <p>A GABA-B agonist that hyperpolarizes cells</p> Signup and view all the answers

    Milrinone increases cardiac contractility by which mechanism?

    <p>Both A and B</p> Signup and view all the answers

    PKA increases cardiac contractility via which mechanism?

    <p>Coordinated response to increase Ca++ cycling</p> Signup and view all the answers

    Which factor is NOT involved in alpha 1 adrenergic receptor signaling?

    <p>Vasodilation</p> Signup and view all the answers

    Study Notes

    Question 1

    • SNS receptors use nAchR preganglionic and norepinephrine postganglionic receptors

    Question 2

    • Increased blood pressure leads to increased SNS activation and decreased PNS activation.

    Question 3

    • Acetylcholine receptors on endothelium cause vasodilation via NO signals

    Question 4

    • ADH directly activates the release of renin from juxtaglomerular cells. It also activates V2 receptors to increase water absorption in the kidney.

    Question 5

    • Release of calcium from the sarcoplasmic reticulum in cardiomyocytes is due to the ryanodine receptor. Reuptake is handled by SERCA.

    Question 6

    • Vascular resistance is inversely proportional to the radius to the 4th power

    Question 7

    • Aldosterone, Angiotensin II, and ADH are directly increased with SNS activity. ANP is not directly increased.

    Question 8

    • Natriuretic peptides exert intracellular effects through cGMP production and PDE3 inhibition.

    Question 9

    • Increased cardiac contractility will not be explicitly stated in this passage.

    Question 10

    • Hydralazine may reduce blood pressure by decreasing ROS, activating potassium channels, and inhibiting the IP3 receptor.

    Question 1 (Last Quiz)

    • Activation of M3-AchRs on lung bronchial smooth muscles causes bronchoconstriction

    Question 2

    • On vascular smooth muscle, alpha 1 adrenergic signals cause vasoconstriction and beta 2 signals cause vasodilation.

    Question 3

    • Succinylcholine activates nAchR causing muscle activity, quickly, but the activation desensitizes nAchR signaling and reduces muscle activity.

    Question 4

    • Non-depolarizing neuromuscular junction blockers are not listed.

    Question 5

    • Baclofen is a GABA-B agonist that hyperpolarizes cells and reduces excitatory signals or reduces Ca++ influx.

    Question 6

    • Milrinone increases cAMP in the heart and increases contractility and inhibits PDE3.

    Question 7

    • PKA increases cardiac contractility by coordinating a response to increase Ca++ cycling (RyR2, LTCC, and PLB) phosphorylation, directly phosphorylating cardiac TnC, and increasing MLC phosphorylation via MLCK.

    Question 8

    • The correct order (highest to least) for affinity of alpha1 adrenergic receptors is phenylephrine, norepinephrine, epinephrine, dopamine.

    Question 9

    • Active PKG in vessels may reduce MLC phosphorylation (by activating myosin phosphatase and K+ channels) and reduce Ca++ channel activities, block vascular PKA activity to cause vasodilation, and increase cGMP to cause vasodilation.

    Question 10

    • Activation of beta2 adrenergic receptors increases vasodilation and bronchodilation through PKA activity

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    BPS337 Exam 4 to Final Quizzes PDF

    Description

    This quiz covers key concepts in the physiology of the autonomic nervous system, particularly focusing on the roles of neurotransmitters and hormones in cardiovascular regulation. Test your understanding of sympathetic and parasympathetic interactions, receptor functions, and renal hormone regulation.

    More Like This

    Cardiovascular Drugs Quiz
    5 questions

    Cardiovascular Drugs Quiz

    FaultlessGenius avatar
    FaultlessGenius
    Human Cardiovascular Physiology Quiz
    19 questions

    Human Cardiovascular Physiology Quiz

    SafeMilwaukee avatar
    SafeMilwaukee
    Cardiovascular Part 2: CO, HR, SV, Blood Distribution & BP
    77 questions

    Cardiovascular Part 2: CO, HR, SV, Blood Distribution & BP

    RejoicingSuccess avatar
    RejoicingSuccess
    Cardiovascular Physiology Quiz
    80 questions

    Cardiovascular Physiology Quiz

    TougherDerivative avatar
    TougherDerivative
    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser