BMS100 Carbohydrates Metabolism Pre-Learning PDF

Carbohydrates metabolism Pre-learning – review of glycolysis and gluconeogenesis Dr. Rhea Hurnik BMS100 Plan Pre-learning Review Glycolysis and Gluconeogenesis In-class Glycolysis continued Regulation of glycolytic Metabolism of other monosaccharides Gluconeogenesis continued Regulation of gluconeog...

Carbohydrates metabolism Pre-learning – review of glycolysis and gluconeogenesis Dr. Rhea Hurnik BMS100 Plan Pre-learning Review Glycolysis and Gluconeogenesis In-class Glycolysis continued Regulation of glycolytic Metabolism of other monosaccharides Gluconeogenesis continued Regulation of gluconeogenic enzyme Pentose phosphate shunt General pathway Regulation Glycogenesis & Glycogenolysis General pathways Regulation Learning outcomes Diagram the connections between glycolysis, gluconeogenesis, pentose phosphate shunt, glycogenesis, and glycogenolysis Glycolysis § Briefly review glycolysis, including reactants & products, enzyme names, and any allosteric and hormonal regulators of the enzymes. Irreversible steps of glycolysis are testable on the next quiz, test, and final exam, include substrate, product, enzyme, and enzyme regulation § Describe the metabolism of fructose and how it feeds into glycolysis Gluconeogenesis § Briefly review gluconeogenesis, including reactants & products, enzyme names, and any allosteric and hormonal regulators of the enzymes Bypass reactions of gluconeogenesis are testable on the next quiz, test, including substrate, product, enzyme, and enzyme regulation § Note: Gluconeogenic substrates are testable on the final exam. Describe the pentose phosphate shunt include starting substrates and glycolytic products. § Describe the key product of the pentose phosphate shunt, including NADPH and pentose phosphates § Describe the allosteric and hormonal regulation of glucose-6-Phosphate dehydrogenase Outline glycogenesis and glycogenolysis pathways, including key enzymes involved. § Describe allosteric and hormonal regulation of glycogen synthase and glycogen phosphorylase Plan Pre-learning Review Glycolysis and Gluconeogenesis using the questions on the following slides There is no video for the following slides, refer back to your glycolysis and gluconeogenesis lectures for the correct answers. For the next quiz, test, and the final exam – you will be responsible for knowing the details asked in subsequent slides Glycolysis - 1 Where in the cell does glycolysis take place? What is the starting substrate and final end products of glycolysis § How many net ATP are gained from substrate level phosphorylation? § Is there any indirect energy gained from glycolysis Where does this molecule go next? Glycolysis - 2 List the three irreversible reactions of glycolysis, including the substrate, enzyme, and product Gluconeogenesis - 1 Where in the cell does gluconeogenesis take place? What tissue(s) in the body use gluconeogenesis. What are the three bypass reactions of gluconeogenesis § Include substrate, enzyme, and product Gluconeogenesis - 2 What are the three substrates of gluconeogenesis § Where do they enter the gluconeogenesis pathway? Draw out the cori cycle