Central Dogma of Cytology and Molecular Biology PDF

# Central Dogma of Cytology and Molecular Biology - DNA Transcription mRNA Translation Protein - Cell specific - "interphase nucleus" - DNA don't leave the nucleus - Reverse Transcription -> RNA turns into DNA - Prior to Cell Division occur Replication - 46 chromosomes -> 92 chromosomes - C...

# Central Dogma of Cytology and Molecular Biology - DNA Transcription mRNA Translation Protein - Cell specific - "interphase nucleus" - DNA don't leave the nucleus - Reverse Transcription -> RNA turns into DNA - Prior to Cell Division occur Replication - 46 chromosomes -> 92 chromosomes - Central Dogma: - Relation ship and interaction among the three major molecules recruited "inheritance" ### Genome "100%" ### Cell Specific ### Euchromatine 2% ### Gene Expression - Transcription - mRNA < DNA "Gene Ex. Pression" - occurs within cell nucleus - copying small sequences of mRNA ### Procedure 1 - un coil DNA dh by helicase 2 - RNA Polymerase Fit nucleated of mRNA - Non sens strand (5' 3') - sense strand (3' 5') - RNA Polymerase (3' 5') - Promoter - Transition - Termination - Regain - mRNA (mature) - introns - exons ## Post Transcriptional Modifications - DNA splicing - splicing refers to the joining all exons and removing introns - 7-methyl Guanosine - Poly Adenylation - Capping # Increase Life Span - Protect mRNA molecule from degradation - mRNA molecule leave nucleus through nuclear pore, or nuclear membrane