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Questions and Answers
What is the primary function of RNA polymerase during transcription?
What is the primary function of RNA polymerase during transcription?
What is the role of the 7-methyl Guanosine in post-transcriptional modification?
What is the role of the 7-methyl Guanosine in post-transcriptional modification?
During which stage does DNA replication occur?
During which stage does DNA replication occur?
What is the outcome of splicing in mRNA processing?
What is the outcome of splicing in mRNA processing?
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Why is it important for mRNA to exit the nucleus?
Why is it important for mRNA to exit the nucleus?
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What defines the 'sense' and 'non-sense' strands during transcription?
What defines the 'sense' and 'non-sense' strands during transcription?
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What is the central dogma of molecular biology primarily concerned with?
What is the central dogma of molecular biology primarily concerned with?
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Study Notes
Central Dogma of Cytology and Molecular Biology
- DNA transcribes to mRNA; mRNA translates to protein
- DNA remains in the nucleus
- Replication occurs before cell division
- 46 chromosomes (example given)
- Relationship and interaction among the three major molecules involved in inheritance
- Genome (100%)
- Euchromatin (92%)
- Gene Expression
- Transcription to mRNA
Gene Expression
- Occurs within the cell nucleus
- Copying small sequences of mRNA
- Procedure:
- Uncoil DNA using helicase
- RNA polymerase attaches to the DNA to bind and create mRNA
Post-Transcriptional Modifications
- DNA modification after transcription
- Splicing: Joining exons and removing introns
- Polyadenylation: Adding 100-250 adenines
- Capping: Adding GMP + P to GDP + energy
Increased mRNA Lifespan
- Protects mRNA from degradation
- mRNA exits the nucleus through nuclear pores
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Description
Test your understanding of the central dogma of molecular biology, which details the processes of DNA transcription and mRNA translation into proteins. Explore gene expression, post-transcriptional modifications, and the lifespan of mRNA. This quiz covers fundamental concepts crucial for grasping genetic inheritance and manipulation.
