Chapter 1 Immunology PDF

Chap - * immunology body protects -...

Chap - * immunology body protects - itself science that from diseases deals w/ ways infection. of en molecule carrier carojes conjugate se not ↓ # Immunity-state where the host is induce immune susceptible (invulnerable) to inf & disease response -Active vs passive immunity epitope/antigence determinant-active regions of antigen ACTIVE Passive that combines products + spec immune response Antibodies INSIDE of introduce from antigens o structurally complex (contain diff - produce - OUTSIDE of body - body epitopes. Results Direct infection mother-baby by IS antibodies to several responds by producing - · · from vaccination placent a epitopes · on Ag. · breast milk & antigenicity vs immunogenicity · therapeutre · antigenicity - ability to combine specifically of injection of EX secreted ab/ products : immune response. Ovetimeplease Takes Immediately surfacereceptors on T cells. affect ( IR Immunogenicity ability to induce · - lenght of long-term > - short-term · All molecules have immunogenicity: antigenicity efficacy lifelong · molecules have antigenicity of immunogenicity. Generates no ↳ chemical nature of yes immunogens cells Proteins of the vast majority · memory immunogens - ↳ 2 types of proteins/glycoproteins / immune system pure lipo proteins. - Innate immediately 1 immune system respond a Polysaccharides -. & & initrate there acrds-poor Adaptive. 2 immune nucleic but system · immunogenic - when immunogenie in single strand/complex proteins activities #2 types of protection · Lipids-non-immunogenic , may be haptens 1. Innate Recognition - Immune system distinguish & vs adaptive immunity I selfI non-self Innate Adaptive suited to eliminate non-specifie immit the specific immunity responseeachresponse 2 oantigent o · 1st 9 Ind line defense 3od line defense dependent · · bus non specifie Antigen independent & Actx attribute to immune system · · antigen immunity defending against invading pathogens acquired ·. · not immunity · delay maximal response out' · removing worn cells & tissues dog · no immunological memory (presence of lag time o identifying I destroying abnormal/mutant cells · immediate maximal response · produce immunological memory of line · invatrating inapproporate immune responses lead members defense to allergies/autoimmune disease · 1st line (barrier at body surface) S # Immunogen - substance includes a specific - skin - reflexes womit) normal immune response - (Kunci'y bolch bulself mucous membranes - - (saliva , & Antigen-foreign molecule that specifically bind - Secretions mucus / microbes Innate to antibodies/receptor to induce specific · 2nd line (process) (nonspecifie immune (mem tak Inflammation interferon y - response kunci masula tapi - - bolch boleh bukal NK cells immunity small molecule # Hapten- that incapable causing -phagocytes - w/ fever action immune respond when combine - carried complement - protein. = system All antigen immunogen are · 3rd line Y T cell acquired - lymphocytes B cell Especifie - Antibodies immunity ( - Innate Adaptive & B cell macrophage (primary WBC) · Natural kill cell Tcell * Antibodies i e tic · TcIl M cell phil · CD4 Tcl) + CD8 Tcell + Basophil