Podcast
Questions and Answers
What is the primary focus of immunology?
What is the primary focus of immunology?
- To understand how the body protects itself from diseases (correct)
- To analyze the chemical composition of molecules
- To study the genetic makeup of organisms
- To explore the nutritional needs of the immune system
What is active immunity?
What is active immunity?
- A state of immunity where the host can easily be infected
- Immunity gained from the introduction of antibodies from another organism
- A temporary immunity gained through exposure to a disease
- Immunity developed through the body's own immune responses (correct)
What does passive immunity involve?
What does passive immunity involve?
- Long-term immunity developed through vaccination
- Introduction of antibodies from an external source (correct)
- Immediate immune response to pathogens
- Production of antibodies by the host
What are epitopes?
What are epitopes?
How does the body develop an immune response?
How does the body develop an immune response?
What is a characteristic of passive immunity?
What is a characteristic of passive immunity?
What best describes the immune state of susceptibility?
What best describes the immune state of susceptibility?
What is the role of antibodies in the immune response?
What is the role of antibodies in the immune response?
Which statement about antigens is correct?
Which statement about antigens is correct?
Which type of immunity involves the adaptive immune response?
Which type of immunity involves the adaptive immune response?
What is immunogenicity primarily associated with?
What is immunogenicity primarily associated with?
Which of the following terms are often used interchangeably?
Which of the following terms are often used interchangeably?
What do surface receptors on T cells influence?
What do surface receptors on T cells influence?
How is the duration of immunogenicity typically described?
How is the duration of immunogenicity typically described?
Which statement accurately reflects the nature of all molecules concerning immunogenicity?
Which statement accurately reflects the nature of all molecules concerning immunogenicity?
What is NOT a characteristic of long-term immunogenicity?
What is NOT a characteristic of long-term immunogenicity?
Which aspect of immunogenicity is closely tied to the efficacy of a molecule?
Which aspect of immunogenicity is closely tied to the efficacy of a molecule?
What influence do T cell surface receptors have in the immune system?
What influence do T cell surface receptors have in the immune system?
What is the primary distinction between antigenicity and immunogenicity?
What is the primary distinction between antigenicity and immunogenicity?
Which of the following best describes antigenicity?
Which of the following best describes antigenicity?
In the context of immunology, what does 'therapeutre' likely refer to?
In the context of immunology, what does 'therapeutre' likely refer to?
Which of the following statements about secreted antibodies (ab) is correct?
Which of the following statements about secreted antibodies (ab) is correct?
What would be an example of a product that is likely to provoke an immune response when injected?
What would be an example of a product that is likely to provoke an immune response when injected?
Which factor is essential for an antigen to be considered immunogenic?
Which factor is essential for an antigen to be considered immunogenic?
How does the concept of antigenicity relate to the effectiveness of vaccines?
How does the concept of antigenicity relate to the effectiveness of vaccines?
What role do secreted antibodies play in the immune system?
What role do secreted antibodies play in the immune system?
What type of immune system responds immediately to invaders?
What type of immune system responds immediately to invaders?
Which type of molecules are known to be non-immunogenic?
Which type of molecules are known to be non-immunogenic?
What characteristic do haptens possess?
What characteristic do haptens possess?
Which immune system component does NOT respond immediately?
Which immune system component does NOT respond immediately?
What type of molecules are regarded as immunogenic?
What type of molecules are regarded as immunogenic?
Which of the following is NOT a characteristic of the innate immune system?
Which of the following is NOT a characteristic of the innate immune system?
Which of these molecules may act as haptens?
Which of these molecules may act as haptens?
What are the types of immune protection primarily provided by polysaccharides?
What are the types of immune protection primarily provided by polysaccharides?
What type of substances are primarily classified as immunogens?
What type of substances are primarily classified as immunogens?
How many types of proteins or glycoproteins are stated to function as immunogens?
How many types of proteins or glycoproteins are stated to function as immunogens?
Which of the following correctly identifies the chemical nature of the majority of immunogens?
Which of the following correctly identifies the chemical nature of the majority of immunogens?
Which of these substances is NOT typically considered an immunogen?
Which of these substances is NOT typically considered an immunogen?
What is the main role of immunogens in the immune system?
What is the main role of immunogens in the immune system?
In the context of the immune system, which category do lipoproteins fall under?
In the context of the immune system, which category do lipoproteins fall under?
What aspect of immunogens is essential for their recognition by the immune system?
What aspect of immunogens is essential for their recognition by the immune system?
Which characteristic is important for a substance to be classified as an immunogen?
Which characteristic is important for a substance to be classified as an immunogen?
What is the primary role of an immunogen?
What is the primary role of an immunogen?
What characterizes innate immunity compared to adaptive immunity?
What characterizes innate immunity compared to adaptive immunity?
Which of the following statements about haptens is true?
Which of the following statements about haptens is true?
What is NOT a characteristic of the 1st line of immune defense?
What is NOT a characteristic of the 1st line of immune defense?
What is the role of NK (Natural Killer) cells in the immune response?
What is the role of NK (Natural Killer) cells in the immune response?
Which of the following describes the concept of immunological memory?
Which of the following describes the concept of immunological memory?
What can inappropriate immune responses lead to?
What can inappropriate immune responses lead to?
Which component is primarily involved in the inflammatory response?
Which component is primarily involved in the inflammatory response?
How does fever function in the body's immune response?
How does fever function in the body's immune response?
What is a common outcome of the maximal immune response?
What is a common outcome of the maximal immune response?
Which of the following is NOT part of the 2nd line of immune defense?
Which of the following is NOT part of the 2nd line of immune defense?
What is one function of complement proteins in immune response?
What is one function of complement proteins in immune response?
What describes the lag time in the immune response?
What describes the lag time in the immune response?
What is a consequence of the presence of immunological memory in a host?
What is a consequence of the presence of immunological memory in a host?
Flashcards
Immunology
Immunology
The science of how the body protects itself from diseases and infection.
Immunity
Immunity
The state where the body is resistant to infection and disease.
Active Immunity
Active Immunity
Immunity acquired through the body's own immune response.
Passive Immunity
Passive Immunity
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Antibodies
Antibodies
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Antigen
Antigen
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Epitope/antigen determinant
Epitope/antigen determinant
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Active regions of the antigen
Active regions of the antigen
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Immune response
Immune response
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Susceptible (invulnerable)
Susceptible (invulnerable)
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Antigenicity
Antigenicity
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Immunogenicity
Immunogenicity
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Breast milk antigenicity
Breast milk antigenicity
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Breast milk immunogenicity
Breast milk immunogenicity
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Injection of secreted antibodies
Injection of secreted antibodies
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Products
Products
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Immunogenicity definition
Immunogenicity definition
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Long-term efficacy
Long-term efficacy
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Short-term efficacy
Short-term efficacy
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Immunogenicity of molecules
Immunogenicity of molecules
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Surface receptors on T cells
Surface receptors on T cells
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Immunogenicity & Antigenicity
Immunogenicity & Antigenicity
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Lifelong efficacy
Lifelong efficacy
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What are immunogens?
What are immunogens?
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What is the chemical nature of most immunogens?
What is the chemical nature of most immunogens?
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What are the two main types of immunogens?
What are the two main types of immunogens?
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Are all proteins immunogens?
Are all proteins immunogens?
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What are lipoproteins?
What are lipoproteins?
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Are lipoproteins immunogens?
Are lipoproteins immunogens?
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What does 'pure' mean in the context of immunogens?
What does 'pure' mean in the context of immunogens?
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Why are pure immunogens important?
Why are pure immunogens important?
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Innate Immunity
Innate Immunity
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What are the two types of immune responses?
What are the two types of immune responses?
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What makes a substance immunogenic?
What makes a substance immunogenic?
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What makes a substance non-immunogenic?
What makes a substance non-immunogenic?
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Haptens
Haptens
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What are some examples of immunogenic substances?
What are some examples of immunogenic substances?
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What is the difference between an immunogen and antigen?
What is the difference between an immunogen and antigen?
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Immunogen
Immunogen
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What are the main lines of defense in the immune system?
What are the main lines of defense in the immune system?
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First line of defense
First line of defense
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Second line of defense
Second line of defense
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Third line of defense
Third line of defense
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What are the characteristics of the innate immune response?
What are the characteristics of the innate immune response?
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What are the characteristics of the adaptive immune response?
What are the characteristics of the adaptive immune response?
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What is immunological memory?
What is immunological memory?
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What are the consequences of inappropriate immune responses?
What are the consequences of inappropriate immune responses?
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What is inflammation?
What is inflammation?
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What are the roles of NK cells and phagocytes in immunity?
What are the roles of NK cells and phagocytes in immunity?
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Study Notes
Chapter 1: Immunology
-
Immunology: Science of how the body defends itself against disease
-
Immunity: State of being protected from a disease due to prior exposure; resistance to infection
-
Active Immunity: Body produces its own antibodies
- Develops after exposure to the antigen
- Long-lasting, often lifelong
- Examples: Infection, vaccination
-
Passive Immunity: Antibodies obtained from an outside source
- Short-term protection
- Examples: Maternal antibodies, antibody injections
Active vs. Passive Immunity
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Active: Body produces antibodies
- Mechanism: Direct infection, vaccination
- Duration: Long-term
- Response: Gradual building of immunity
-
Passive: Antibodies are transferred
- Mechanism: Mother to baby (placenta, breast milk), therapeutic injections
- Duration: Short-term
- Response: Immediate but temporary protection
Antigens vs. Antibodies
-
Antigens: Molecules stimulating an immune response
- Often complex structures, typically proteins or carbohydrates
- Have specific sites (epitopes) recognized by antibodies
- Can be foreign (pathogens) or self (autoimmune)
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Antibodies (Immunoglobulins): Specialized proteins; bind to antigens
- Recognize and neutralize specific antigens
- Crucial for antibody-mediated immunity
Immunogenicity vs. Antigenicity
- Antigenicity: Ability of a substance to combine with antibodies & T-cell receptors
- Immunogenicity: Ability to induce an immune response
Types of Immune Systems
-
Innate Immune System: Rapid, non-specific response. - First and second line of defense - No memory or prior sensitization - Components: Physical barriers, phagocytes, inflammation, fever
-
Adaptive Immune System: Specific, slower response. - Third line of defense - Exhibits a "memory" capacity, stronger response to subsequent exposure - Components: Lymphocytes, antibodies
Innate Immunity (Non-specific)
- Attributes: Immediate defense; broad range, non-specific actions.
- Components: Physical barriers, phagocytes, inflammation, fever, natural killer (NK) cells
- Effective against wide range of pathogens.
- No memory of pathogens.
Adaptive Immunity (Specific)
- Attributes: Develops after exposure; highly specific.
- Components: B cells, T cells, and antibodies
- Mechanism: Recognizes specific antigens; has memory cells
- Response: More potent, and better response at second encounter of pathogen.
Cellular Components of the Immune System (Page 2)
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Innate: Natural killer (NK) cells, macrophages, neutrophils, dendritic cells, eosinophils, basophils, mast cells, complement system
-
Adaptive: B cells, T cells
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Types of T cells: Helper T cells (CD4+), Cytotoxic T cells (CD8+)
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Types of B cells: Plasma cells (antibody production)
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