Polypharmacy Lecture Notes PDF

Polypharmacy Clinical Sciences IV Geriatrics Paul B. Volker, MD, FAAFP Assistant Professor Department of Family and Internal Medicine 1 April 2024 Disclosures I hold no professional or remunerative relationships with pharmaceutical or medical equipment manufacturers No off-label drug recommendations...

Polypharmacy Clinical Sciences IV Geriatrics Paul B. Volker, MD, FAAFP Assistant Professor Department of Family and Internal Medicine 1 April 2024 Disclosures I hold no professional or remunerative relationships with pharmaceutical or medical equipment manufacturers No off-label drug recommendations Generic drug names or classes will be used on the test; brand names will also be mentioned in the lecture where appropriate Some slides are used with permission from the American Geriatrics Society 1 April 2024 Volker Geriatrics Polypharmacy 2 Objectives Explain the principles of prescribing for older patients Explain the risks to patient health and monetary costs associated with polypharmacy Explain the concepts of pharmacokinetics and pharmacodynamics and how they apply specifically to the relatively contraindicated drug classes Give examples of “good” or “necessary” polypharmacy List the similarities and differences in polypharmacy in younger and older adults List specific classes of drugs relatively contraindicated in the geriatric population Describe the history, importance, and application of Beers’ Criteria 1 April 2024 Volker Geriatrics Polypharmacy 3 The use of multiple medications, indicated or not, in a patient with multiple medical problems (the multimorbid patient). Often a term used to suggest the overprescribing or overuse of medication in a patient. POLYPHARMACY 1 April 2024 Volker Geriatrics Polypharmacy 4 Outline for These Two Lectures Polypharmacy: Is there a problem? Age-associated changes in pharmacokinetics and pharmacodynamics Adverse Drug Effects Beers Criteria Principles of prescribing and deprescribing 1 April 2024 Volker Geriatrics Polypharmacy 5 Yes, there is… POLYPHARMACY OVERVIEW IS THERE A PROBLEM? 1 April 2024 Volker Geriatrics Polypharmacy 6 Why Geriatric Pharmacotherapy is Important Now, people age 65+ are 13% of US population, buy 33% of prescription drugs 2020 People>65 Prescriptions People>65 1 April 2024 People