Toxicity Testing - PDF
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Uploaded by ThankfulAutomatism2060
Universiti Putra Malaysia
Rozaini binti Abdullah
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Summary
This presentation discusses toxicity testing, covering topics such as in vivo and in vitro testing, regulatory aspects, and different types of tests like acute, sub-acute, and chronic toxicity tests. The presentation also includes a history of toxicity studies and good laboratory practices (GLP).
Full Transcript
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2 3 4 5 6 Pa 7 8 9 10 11 12 13 14 15 16 17 ( watea 18 19 20 21 en sich * asplita o in mo e ·o 22 23 if chem y ( another chem) cause lower growth compared to control group, adakan it is a mutagent? No, sbb mutagent akan increase kn growth histiden tht hv been mutated tht it wont growth sny if those histidenine is growing after mix wif chem, the chem cause mutation - jdi grow so, the chemnis a mutagent pro-mutagen : non direct acting mutagent need to be metabolized first b4 it can convert his- to his+ 24 - sta i a & acrodite o a we are - 25 26 27 28 29 Rozaini Dec 2009-2012 30 31 32 the longer the tail, the more dna damage occur hot all dna damage cause mutation because if its being repaired, then it will not being mutate 33 34
