Mutagenicity and Types of Mutagens

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Questions and Answers

What would be the conclusion if a chemical causes lower growth compared to the control group?

  • The chemical needs to be metabolized first
  • The chemical has no effect on growth
  • The chemical is not a mutagen (correct)
  • The chemical is a mutagen

What is the term for a non-direct acting mutagen that needs to be metabolized first?

  • Mutagen
  • Chemical agent
  • Histidine
  • Pro-mutagen (correct)

What would be the conclusion if histidine grows after mixing with a chemical?

  • The chemical has no effect on histidine
  • The chemical needs to be metabolized first
  • The chemical is a mutagen (correct)
  • The chemical is not a mutagen

What is the effect of a mutagen on the growth of mutated histidine?

<p>It increases the growth (A)</p> Signup and view all the answers

What is the role of metabolic activation in a pro-mutagen?

<p>It converts the pro-mutagen into a mutagen (B)</p> Signup and view all the answers

What is the result if a chemical causes an increase in the growth of mutated histidine?

<p>The chemical is a mutagen (C)</p> Signup and view all the answers

What is the definition of a mutagen?

<p>A substance that increases the growth of mutated histidine (B)</p> Signup and view all the answers

What is the role of a mutagen in the growth of histidine?

<p>It increases the growth of mutated histidine (A)</p> Signup and view all the answers

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Study Notes

Mutagenicity

  • A mutagen is a chemical that causes an increase in growth due to mutations.
  • If a chemical causes lower growth compared to the control group, it is not a mutagen.
  • Mutagens increase growth by causing mutations in histidine, which then grow.

Direct and Indirect Acting Mutagens

  • A mutagen can be direct or indirect acting.
  • Pro-mutagen is a non-direct acting mutagen that needs to be metabolized first before it can convert histidine to its mutated form (his+).

Note on Research

  • Rozaini conducted research on mutagenicity from 2009 to 2012.

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