Unit 10 Topical Agents PDF

UNIT 10 | TOPICAL AGENTS Protective Properties Uses burn SKIN Talc Native hydrous ★...

UNIT 10 | TOPICAL AGENTS Protective Properties Uses burn SKIN Talc Native hydrous ★ Filtering Aluminum stimulate tissue growht magnesium silicate agent Foil Functions: (3MgO.4SiO2.H2O) ★ Dusting 1. 1st line of defense against pathogens powder Aluminum Prevent irritation *pathogens -> disease-causing Paste around intestinal 2. Protection Contraindication: fistulae Broken skin/Open -> Protects skin from wound -> sterile digestive action of TOPICAL AGENTS abscess and granuloma intestinal fluids Calamine Primary Ing: used in open wounds/ gastrointestinal Compounds used on body surfaces Zinc Oxide wound exuding fluid fistula Effect on epithelial surfaces / local effect - Abnormal opening in Route of administration: directly applied Pink Coloration: the digestive tract Localized effect Ferric Oxide causes gastric fluids to ○ Occurs at site of application seep through the lining Systemic effect May be phenolated of your stomach or ○ Wider impact, affect 2 or more organs (1%) to give intestines or stomach Are sheetmasks topical? YES Antipruritic effect & acid leaking out. Are intradermal agents topical? NO anti-itch effect Is mouthwash topical? YES Silicon Simeticone gastroprotective Polymer PROTECTIVES Zinc Advantages: For wounds Stearate - Not wetted by discharging moisture large amounts Main Properties: - Does not form of fluids ★ Chemically Inert crusty patches lubricant in ○ Prevent irritation on skin manufacturin ★ Insoluble Disadvantages, If g of tablets ○ Difficult to wash out inhaled: Sub for talc as Applied as dusting powders, suspensions or - pulmonary damage dusting ointments -hemorrhage powder Compounds applied to the skin to protect from irritation or internally for GI irritations Titanium Reflectant Dioxide -> Screens out UV Rad Aluminum - protective agt for  Supplemental References: ANTIMICROBIALS 4. Antinomy properties of the 1. mechanisms of antibacterial drugs protein or will result to precipitating the Term Meaning protein precipitant Antiseptic any agent that kills or inhibits the growth of microorganisms on living tissue. ASTRINGENTS Disinfectant any agent which destroys microorganisms on inanimate objects Diluted solutions Limited penetration power Sterilization completely free from microorganisms “tightening” of tissue Uses: ○ Styptic Stops bleeding Compounds Mechanism ○ Antiperspirant involved ○ Corrosive ○ Anti-inflammatory Oxidation 1. Iodine Effective oxidative 1. Aluminum Salts 2. Chlorine action of these 2. Soluble Zinc Compounds 3. Potassium compounds: 3. Toughened Silver Nitrate permanganate - reducing groups 4. Hydrogen present in most peroxide proteins (sulfhydryl groups). The overall change or destructive function in specific proteins is responsible for the ultimate death of the microorganism. Halogenation Hypochlorite Substitution of the chlorine atom for the hydrogen -> changes in the bonding = destruction of microbes. Protein 1. Silver complexation of the Precipitation 2. Mercury metal results in the 3. Sulfur radical change in the