Lipids and Lipoproteins Learning Objectives PDF

Lipids and Lipoproteins ======================= Learning Objectives =================== Recall ------ 1. Describe the function of lipids. 2. Describe the major classes of lipids including sources in the body, structure, and function - Fatty Acids - Triglycerides - Phos...

Lipids and Lipoproteins ======================= Learning Objectives =================== Recall ------ 1. Describe the function of lipids. 2. Describe the major classes of lipids including sources in the body, structure, and function - Fatty Acids - Triglycerides - Phospholipids - Cholesterol & Cholesteryl esters 3. Explain the function, size, density, lipid content, and associated Apo proteins for the following - Chylomicrons - VLDL - LDL - HDL 4. Explain the function and origin for the following Apolipoproteins - Apo A-I - Apo B - Apo B-100 - Apo B-48 - Apo CII - Apo D - Apo E 5. Describe the pathways of lipid metabolism - Absorption - Exogenous - Endogenous - Reverse cholesterol transport 6. Explain factors that can affect cholesterol levels. 7. Identify the methodology, specimen of choice, and interfering substances for measuring - Cholesterol - Triglyceride - HDL. 8. Describe the criteria and clinical significance of metabolic syndrome. 9. Describe the process of atherosclerotic plaque formation. 10. Define - Xanthoma - Micelle - Plaque - Dyslipidemia - Hyperlipoproteinemia - Hypolipoproteinemia - Arteriosclerosis Application ----------- 11. Calculate and explain the Friedewald formula including limitations. 12. Calculate and explain the clinical significance of non-HDL cholesterol. 13. Identify causes, symptoms, and interpret laboratory tests for the following - Hyperlipoproteinemia - Hypolipoproteinemia - Hypercholesterolemia - Hypertriglyceridemia - Combined Hyperlipoproteinemia