Thoracic Pathology Lecture Notes PDF
Document Details
2023
Sofia Mincolelli
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Summary
This lecture covers obstructive and interstitial lung diseases, including chronic bronchitis, emphysema, asthma, and bronchiectasis. It also provides an overview of infections and lung tumors. The material is detailed, but students should focus on understanding the meanings and importance of pathological findings for diagnoses.
Full Transcript
Thoracic Pathology -- prof. Tallini Lesson \#1 -- 30.03.2023 Sbobinatore: Sofia Mincolelli Reviewer: Virginia Calcagni **Pathology of the Lung -- Obstructive and Interstitial (Acute) Disorders.** Program of thoracic pathology - Diseases of the respiratory system; - Pathology of the thymus...
Thoracic Pathology -- prof. Tallini Lesson \#1 -- 30.03.2023 Sbobinatore: Sofia Mincolelli Reviewer: Virginia Calcagni **Pathology of the Lung -- Obstructive and Interstitial (Acute) Disorders.** Program of thoracic pathology - Diseases of the respiratory system; - Pathology of the thymus and mediastinum; - Pathology of the breast. *Note of the sbobinatore: information written in italics were not directly mentioned in class by the professor this year, but were present in past year sbobina/in the slides.* **DISEASES OF THE RESPIRATORY SYSTEM** [Lung pathologies] can be subdivided into the following categories: - Anatomic alterations and histopathology of **obstructive pulmonary diseases** (chronic bronchitis, emphysema, asthma, bronchiectasis); - Anatomic alterations and histopathology of **interstitial lung disease**: diffuse alveolar damage and acute interstitial lung diseases, chronic interstitial lung diseases (fibrosing, granulomatous, eosinophilic, other); - **Diffuse alveolar hemorrhage**: syndromes and histopathology; - Anatomic alterations and histopathology of **infectious pneumonia**: general features, lobar pneumonia, bronchopneumonia, viral/infectious interstitial pneumonia, tuberculosis; - **Lung tumors**: general features, staging, molecular pathology, classification and histopathological diagnosis (squamous carcinoma, adenocarcinoma, neuroendocrine tumors, other neoplasms); - **Pleural tumors**: solitary fibrous tumors, malignant mesothelioma. *Professor said that the material we are provided with is very detailed, but for the exam most of those details are not necessary. What is important is to show we've grasped the meaning and the importance of pathological findings for the diagnosis of disorders of the respiratory system.* This lecture will be focusing on obstructive pulmonary diseases and introducing interstitial lung diseases. The respiratory pathology course will be divided into the following sections: 1. **Non-neoplastic lung diseases**: - Lung anatomy and microanatomy → imaging; - Lung physiology; - Clinical picture (acute vs. chronic); - Pathology. 2. **Neoplastic lung diseases**: - Pathology of lung carcinoma; - Pathology of pleural tumors. **Respiratory Tract Anatomy and Micro-Anatomy** ![](media/image2.png)Starting from the trachea, the respiratory tract is progressively bifurcated, ending in terminal bronchioles ***(\~\