Pharm PUD/GERD Medication List PDF
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Augsburg University
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This document contains a list of questions and answers on various medications used to treat peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). It covers mechanisms of action, adverse effects, and interactions, providing comprehensive information for students studying pharmacology.
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1. What is the mechanism of action of amoxicillin? a) Inhibits bacterial cell wall synthesis b) Blocks DNA gyrase c) Inhibits protein synthesis d) Binds to 50S ribosomal subunit Answer: a) Inhibits bacterial cell wall synthesis 2. Which adverse effect is most commonly associated with metronidazole?...
1. What is the mechanism of action of amoxicillin? a) Inhibits bacterial cell wall synthesis b) Blocks DNA gyrase c) Inhibits protein synthesis d) Binds to 50S ribosomal subunit Answer: a) Inhibits bacterial cell wall synthesis 2. Which adverse effect is most commonly associated with metronidazole? a) Photosensitivity b) Disulfiram-like reaction with alcohol c) QT prolongation d) Black tongue Answer: b) Disulfiram-like reaction with alcohol 3. Which class does clarithromycin belong to? a) Beta-lactams b) Macrolides c) Tetracyclines d) Nitroimidazoles Answer: b) Macrolides 4. What is a contraindication for tetracycline use? a) Renal failure b) Pregnancy c) Hypocalcemia d) Anemia Answer: b) Pregnancy 5. What is the mechanism of action of bismuth? a) Inhibits proton pumps b) Forms a protective barrier over ulcers c) Neutralizes stomach acid d) Enhances gastric motility Answer: b) Forms a protective barrier over ulcers 6. Which medication is a calcium carbonate antacid? a) Maalox b) Tums c) Nexium d) Carafate Answer: b) Tums 7. What adverse effect is most commonly associated with aluminum hydroxide? a) Diarrhea b) Constipation c) Hyperphosphatemia d) Hypocalcemia Answer: b) Constipation 8. What is the primary adverse effect of long-term cimetidine use? a) Gynecomastia b) Renal impairment c) Myopathy d) QT prolongation Answer: a) Gynecomastia 9. Which indication is appropriate for metoclopramide? a) GERD b) Constipation c) C. difficile infection d) Peptic ulcer disease Answer: a) GERD 10. What is the mechanism of action of omeprazole? a) Inhibits histamine receptors b) Blocks H+/K+ ATPase in parietal cells c) Enhances prostaglandin synthesis d) Neutralizes gastric acid Answer: b) Blocks H+/K+ ATPase in parietal cells 11. What adverse effect is commonly associated with esomeprazole? a) Hypercalcemia b) Vitamin B12 deficiency c) Photosensitivity d) Gynecomastia Answer: b) Vitamin B12 deficiency 12. Which drug forms a protective barrier over ulcers? a) Sucralfate b) Omeprazole c) Bismuth d) Metoclopramide Answer: a) Sucralfate 13. What is a contraindication for misoprostol? a) Hypotension b) Pregnancy c) Diabetes d) GERD Answer: b) Pregnancy 14. Which infection is amoxicillin commonly used to treat in combination therapy? a) C. difficile b) H. pylori c) E. coli d) S. aureus Answer: b) H. pylori 15. What is the major interaction of metronidazole? a) Increases warfarin toxicity b) Decreases statin efficacy c) Inhibits proton pumps d) Induces liver enzymes Answer: a) Increases warfarin toxicity 16. What monitoring is needed for long-term use of omeprazole? a) Renal function b) Vitamin B12 levels c) Blood pressure d) Thyroid function Answer: b) Vitamin B12 levels 17. Which drug class does cimetidine belong to? a) Proton pump inhibitors b) H2 receptor antagonists c) Antacids d) Gastroprotective agents Answer: b) H2 receptor antagonists 18. What is a common adverse effect of misoprostol? a) Uterine contractions b) Black stools c) Tardive dyskinesia d) Constipation Answer: a) Uterine contractions 19. Which medication can cause black stools as a side effect? a) Sucralfate b) Bismuth c) Calcium carbonate d) Metronidazole Answer: b) Bismuth 20. What is the primary mechanism of action of tetracycline? a) Inhibits bacterial protein synthesis b) Disrupts bacterial DNA c) Inhibits bacterial cell wall synthesis d) Neutralizes bacterial toxins Answer: a) Inhibits bacterial protein synthesis