L11_ Mutation II Lecture Notes PDF

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Document Details

StylizedVitality6510

Uploaded by StylizedVitality6510

Vision College of Medicine

Dr.Ezat Mersal

Tags

hemoglobin disorders clinical consequences medical genetics lecture notes

Summary

Lecture notes on mutation II: Clinical Consequences of Hemoglobin Disorders, covering hemoglobin structure, types of adult hemoglobin, thalassemia and sickle cell anemia. The lecture details the causes and effects of these conditions.

Full Transcript

SE WEE Not enough If E It e The issue is in the see if only one Gene from the parent Minorthalasmia i_dIde Joe T...

SE WEE Not enough If E It e The issue is in the see if only one Gene from the parent Minorthalasmia i_dIde Joe Type of hemoglobin that has 4 gama size is smaller than normal one of the gene is normal need blood transfusion Four genes will produce Alla miss e For only 2 gene will produce Alpha I beta will complete the chain 4 gammas complete the chain Beta is produced at the end so will be discovered after Birth Alpha is main so if not produced the fetus will not survive e I

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