From Cell to Tumor PDF Presentation (13/12/2024)

Cell Tumor SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT From Cell to Tumor Bruno Cardoso 13/12/2024 SHAPING THE FUTURE OF MEDICAL EDUCATION...

Cell Tumor SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT From Cell to Tumor Bruno Cardoso 13/12/2024 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  Cancer: a worldwide problem 3 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  Cancer: a nationwide problem 4 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  Cancer: a worldwide problem 5 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  Cancer: a nationwide problem 6 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  Cancer: a worldwide problem 7 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  Cancer: from cell to tumor… Cancer: from cell to tumor… The cell is the basic structural and functional unit of life forms. Every cell consists of a A neoplasm is a type of abnormal and excessive growth of tissue. The process that occurs to cytoplasm enclosed within a membrane, and contains many biomolecules such as proteins, form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated DNA and RNA, as well as many small molecules of nutrients and metabolites. (…) Cells can with that of the normal surrounding tissue, and persists in growing abnormally, even if the acquire specified function and carry out various tasks within the cell such as replication, DNA original trigger is removed. This abnormal growth usually forms a mass, when it may be called repair, protein synthesis, and motility. a tumor. (…) Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an Wikipedia abnormal pattern of growth, such as metaplasia or dysplasia. Wikipedia Cell, in biology, the basic membrane-bound unit that contains the fundamental molecules of Tumour, also spelled tumor, also called neoplasm, a mass of abnormal tissue that arises life and of which all living things are composed. A single cell is often a complete organism in without obvious cause from preexisting body cells, has no purposeful function, and is itself, such as a bacterium or yeast. Other cells acquire specialized functions as they mature. characterized by a tendency to independent and unrestrained growth. Tumours are quite These cells cooperate with other specialized cells and become the building blocks of large different from inflammatory or other swellings because the cells in tumours are abnormal in multicellular organisms, such as humans and other animals. appearance and other characteristics. Britannica Britannica Cells are the basic building blocks of all living things. The human body is composed of Tumors are abnormal growths in your body. (…) Tumors are made up of extra cells. Normally, trillions of cells. They provide structure for the body, take in nutrients from food, convert cells grow and divide to form new cells as your body needs them. When cells grow old, they die, those nutrients into energy, and carry out specialized functions. Cells also contain the and new cells take their place. Sometimes, this process goes wrong. New cells form when body’s hereditary material and can make copies of themselves. your body does not need them, and old cells do not die when they should. These extra cells can MedlinePlus divide without stopping and may form tumor. MedlinePlus The smallest unit of living structure capable of independent existence, composed of a Swelling or morbid enlargement; this is one of the cardinal signs of inflammation. A new growth membrane-enclosed mass of protoplasm and containing a nucleus or nucleoid. Cells are highly of tissue in which cell multiplication is uncontrolled and progressive. Tumors are also called variable and specialized in both structure and function, although all must at some stage neoplasms, which means that they are composed of new and actively growing tissue. Their replicate proteins and nucleic acids, use energy, and reproduce themselves. growth is faster than that of normal tissue, continuing after cessation of the stimuli that evoked medical-dictionary.thefreedictionary.com the growth, and serving no useful physiologic purpose. medical-dictionary.thefreedictionary.com 8 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  Cancer: from cell to tumor… 9 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  From cell to tumor - an overview Process of tumorigenesis Overview p53: the guardian of the genome Hallmarks of Cancer Clonal Evolution 10 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  Process of tumorigenesis HOW DOES IT START??? 11 SHAPING THE FUTURE OF MEDICAL EDUCATION FM.UCP.PT  Peripheral Blood Smear: Clinical Case Increased granulocytes at various stages of differentiation A 45-year-old male presents to the clinic with complaints of Basophilia and eosinophilia observed persistent fatigue, unintentional weight loss of 5 kg over the Bone Marrow Biopsy: past two months, and occasional night sweats. He denies fever, Hypercellular marrow with increased myeloid-to-erythroid ratio bleeding, or significant infections. The patient reports mild left Blasts: