Pathological Physiology Quiz PDF
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Uploaded by ProfuseSard6009
Samarkand State University
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This document contains a set of practice questions and answers related to pathological physiology, covering topics such as fever types, tumour development, pyrogens, and temperature curves in various diseases. The questions are multiple choice format.
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## Pathological Physiology Quiz **Question 6** The center of termoregulation is located in: - a. Hypothalamus - b. Paracentral lobule - c. Cerebral cortex - d. Frontal gyruses - e. Parietal lobe **Question 2** The experimental reproducing of tumour by an ionizing irradiation arises up as a resu...
## Pathological Physiology Quiz **Question 6** The center of termoregulation is located in: - a. Hypothalamus - b. Paracentral lobule - c. Cerebral cortex - d. Frontal gyruses - e. Parietal lobe **Question 2** The experimental reproducing of tumour by an ionizing irradiation arises up as a result: - a. Explantation - b. Isotransplantation - c. Heterotrasplantation - d. Gomotransplantation - e. Productions **Question 7** In what time at the lytical decline of body temperature is falling of it to the norm? - a. Weeks - b. Day and night - c. Month - d. A few hours - e. A few days **Question 16** Polycyclic aromatic hydrocarbons may appear at a metabolic disorders. Their source may be: - a. Vasopressinum - b. Adrenalin - c. Histamine - d. Cholesterol - e. Serotonin **Question 18** What type of fever is observed in the case when a maximum of temperature is observed in the morning, and in the evening it falls to normal or to the subfebrile state? - a. Febris continua - b. Febris intermittens - c. Febris undulans - d. Febris inversa - e. Febris recurrens **Question 5** What cells do produce Interleukin - 1? - a. Enterocytes - b. Thrombocytes - c. Lymphocytes - d. Erythrocytes - e. Monocytes **Question 12** Experimental transplantation of tumour from one animal to other within the limits of one kind is: - a. Heterotrasplantation - b. Isotransplantation - c. Induction - d. Explantation - e. Gomotransplantation **Question 25** What stimulate the innidiation of malignant tumour? - a. Functional anaplasia - b. Appearance fetal antigens - c. Increasing suckling acid - d. Formation of keylones - e. Depressing intercellular contacts **Question 28** How is such type of growth of tumour named, when the accumulations of tumour cells are observed among surrounding tissue, along vessels and nerves? - a. Metastatic - b. Expansive - c. Generalized - d. Proliferative - e. Infiltrative **Question 22** How is the type of fever named, when a gradual fervescence is during set time with the subsequent litic falling it and by the protracted unfever period? - a. Febris intermittens - b. Febris recurrens - c. Febris continua - d. Febris undulans - e. Febris atypica **Question 24** What is a role of lipoid A in pathogenesis of fever? - a. Tertiary pyrogen - b. Primary pyrogen - c. Secondary pyrogen - d. Infection agent - e. By a pyrogen-free matter **Question 29** What substance able to cause a fever is used with a medical purpose? - a. Pyrogenal - b. Glucose - c. Aspirin - d. K chloride - e. Na chloride **Question 30** Choose the pattern of disease at which a maximum of temperature can be observed in the morning, and in the evening it goes down to the normal or subfebrile state? - a. Tuberculosis - b. Croupous pneumonia - c. Malaria - d. Recurrent typhus - e. Lobal pneumonia **Question 31** After introduction of pyrogenal with a medical purpose for a patient a temperature rose, skin became pale, cold to the feel, a chill appeared, the consumption of oxygen increased. What stage of fever is it? - a. Stage of mobilization - b. Stage declines of temperature - c. Stage increasing of temperature - d. Stage of adapted reactions - e. Stage high standing of temperature **Question 26** How do the processes of termoregulation change in the first stage of fever? - a. Heat loss increases - b. Heat production decreases - c. Termoregulation does not change - d. Heat loss decreases - e. Heat loss is equal heat production **Question 34** What disease is characterized an exhausting type of temperature curve? - a. Malaria - b. Croupous pneumonia - c. Lobal pneumonia - d. Sepsis - e. Recurrent typhus **Question 35** The major biochemical feature of tumour cell is: - a. Oppressing of synthesis of nucleic acids - b. Activating of synthesis of phosphotides - c. Activating of synthesis of tricarboxylic acids - d. Activating of synthesis of lipoprotein - e. Activating of synthesis of nucleic acids **Question 31** After introduction of pyrogenal with a medical purpose for a patient a temperature rose, skin became pale, cold to the feel, a chill appeared, the consumption of oxygen increased. What stage of fever is it? - a. Stage of mobilization - b. Stage declines of temperature - c. Stage increasing of temperature - d. Stage of adapted reactions - e. Stage high standing of temperature **Question 33** What type of fever is typical for abdominal typhus in the first period? - a. Febris remittens - b. Febris recurrens - c. Febris intermittens - d. Febris hectica - e. Febris continua **Question 42** What hormones are able to repress the products of endogenous pyrogenous? - a. Tyrosine - b. Somatotropic hormone - c. Oxytocin - d. Prolactin - e. Cortisone **Question 39** What type of fever is related by wide using of antibiotics and antipyretics? - a. Febris recurrens - b. Febris undulans - c. Febris hectica - d. Febris remittens - e. Febris continua **Question 37** What is the correct following of fever stages? - a. Fastigii, decrementi, incrementi - b. Fastigii, incrementi, decrementi - c. Decrementi, fastigii, incrementi - d. Incrementi, decrementi, fastigii - e. Incrementi, fastigii, decrementi **Question 40** That does testify to development of tumour progression during transplantation the animal of Erlich karcinoma? - a. Anaplasia - b. Insensibility to cytostatics - c. Infiltrative growth - d. Unhampered growth - e. Increasing weight of tumour **Question 41** Transference of malignant cells by the blood stream belongs to: - a. Thromboembolism - b. Gas embolism - c. Bacterial embolism - d. Tissue embolism - e. Fatty embolism **Question 44** What type of fever is typical for crupose pneumonia? - a. Febris recurrens - b. Febris hectica - c. Febris remittens - d. Febris intermittens - e. Febris continua **Question 43** Interleukin 1 does not directly act on the neurons of termoregulation centre but realizes through influence on: - a. Prostaglandin E2 - b. Interleukin 1 - c. Interleukin 2 - d. Serotonin - e. Lipoid A **Question 47** Primary pyrogenous, which gets in an organism together with an exciter and enters in the complement of bacterial cells, is: - a. Lipoid A - b. Phosphotides - c. Fatty acids - d. Acids - e. Thyroid hormones **Question 48** What is the third stage of fever named? - a. St. fastigii - b. St. anacroti - c. St. decrementi - d. St. incrementi - e. St. dicroti **Question 49** What type of fever is typical for typhus in the first period? - a. Febris continua - b. Febris hectica - c. Febris remittens - d. Febris recurrens - e. Febris intermittens **Question 45** What are the substances able to cause a fever? - a. Lipopolysaccharides - b. Phosphotides - c. Fatty acids - d. Thyroid hormones - e. Acids **Question 38** What substance helps for development of hyperpyretic fever? - a. Aldosterone - b. Prolactin - c. Somatotropic hormone - d. Cortisone - e. Tyrosin **Question 56** In pathogeny of fever the adjusting point of adjusting of temperature changes under influence: - a. Serotonin - b. Prostaglandin E2 - c. Interleukin 1 - d. Lipoid A - e. Interleukin 2 **Question 51** High correlation in the development of tumours coursed by smouking, is related to influence of chemical carcinogen. What is it? - a. 3,4-benspiren - b. Aflatoxin - c. Ortoaminoazotoluol - d. Dietilnitrozamin - e. Metilkholantren **Question 53** Mechanisms which repress activity of oncogene are named: - a. Mutational - b. Anticellular - c. Immune - d. Cellular - e. Antimutational **Question 54** What type of fever is typical for sepsis? - a. Febris intermittens - b. Febris remittens - c. Febris recurrens - d. Febris hectica - e. Febris continua **Question 59** What is the second stage of fever? - a. St. fastigii - b. St. anacroti - c. St. incrementi - d. St. decrementi - e. St. dicroti **Question 60** In the process of development of fever cells-targets for interleukin 1 are: - a. Lymphocytes - b. Enterocytes - c. Thrombocytes - d. Erythrocytes - e. Neurons **Question 1** Name the type of temperature curve at patient, if the temperature of body rose to 39,7 °C and varies within the limits of 39,0-39,8 °C. - a. Febris recurrens - b. Febris undulans - c. Febris atypica - d. Febris intermittens - e. Febris continua **Question 55** What organ does loss mass less at a cachexy, caused oncodisease? - a. Adipose tissue - b. Liver - c. Heart - d. Spleen - e. Kidney **Question 9** In a patient with cancer of stomach anemia was diagnosed. On the examination of blood smear and bone marrow the signs of megaloblastic bloodforming were found. An insufficient amount of what material may leads to this disorders? - a. Ftor - b. Iron - c. Cholecalciferol - d. Cyanocobalamin - e. Ascorbic acid **Question 41** At which of these diseases is there a type of temperature curve shown in Figure? - a. Rheumatism - b. Sepsis - c. Peritonitis - d. Flu - e. Brucellosis **Question 6** Choose combination of facilities for render of fever in an experiment. - a. Lizard, culture of streptococci - b. Frog, culture of staphylococcuss - c. Rabbit, interleukin-1 - d. Frog, interleukin-1 - e. Guinea-pig, histamine **Question 3** Choose the pattern of disease which an undulans type of temperature curve - a. Recurrent typhus - b. Crupose pneumonia - c. Lobal pneumonia - d. Brucellosis - e. Malaria **Question 44** Which disease is presented in the temperature curve diagram? - a. Peritonitis - b. Malaria - c. Tuberculosis - d. Flu - e. Brucellosis **Question 45** Which disease is presented in the temperature curve diagram? - a. Flu - b. Croupous pneumonia - c. Relapsing fever - d. Active tuberculosis with the collapse of lung tissue - e. Peritonitis **Question 46** Which disease is presented in the temperature curve diagram? - a. Croupous pneumonia - b. Peritonitis - c. Brucellosis - d. Flu - e. Tuberculosis **Question 47** Which disease is presented in the temperature curve diagram? - a. Febris continua - b. Febris inversa - c. Febris hectica - d. Febris recurns - e. Febris remittens **Question 48** What is the type of temperature curve called in figure - a. Febris continua - b. Febris intermittens - c. Febris remittens - d. Febris hectica - e. Febris recurns **Question 10** At the patient with infectious CNS-disease a temperature for a day long is unstable, each 2 hours arrives at different values (higher and below from a norm). What is the most credible reason of day’s fluctuation in the body temperature for this patient? - a. Damage of hypothalamus - b. Disorders of a spinal brain processes - c. Disorders of general circulation - d. Hypoxia - e. Disorders of blood microcirculation **Question 49** Which disease is presented in the temperature curve diagram? - a. Malaria - b. Brucellosis - c. Relapsing fever **Question 50** Which disease is presented in the temperature curve diagram? - a. Febris intermittens - b. Febris recurns - c. Febris continua - d. Febris remittens - e. Febris hectica **Question 8** At patient with the pneumonia has a fever. What biologically active substance does play a leading role in the origin of fever? - a. Serotonin - b. Melatonin - c. Bradykinin - d. Interleukin-1 - e. Prostaglandin E **Question 7** A patient 26 years old was hospitalized to gynaecology department in a grave sepsis condition related to criminal abortion. What type of temperature curve is typical for septic process? - a. Febris intermittens - b. Febris recurrens - c. Febris undulans - d. Febris continua - e. Febris hectica **Question 51** Which disease is presented in the temperature curve diagram? - a. Malaria - b. Brucellosis - c. Relapsing fever - d. Flu - e. Peritonitis **Question 52** The synthesis of interleukin-1 is inducted by: - a. Lipoid A - b. Serotonin - c. Prostaglandines - d. Immunoglobulin - e. Interferon **Question 53** What disease is characterised by the fever of hectica type? - a. Tuberculosis - b. Crupose pneumonia - c. Malaria - d. Lobal pneumonia - e. Recurrent typhus **Question 4** In a patient with the cancer of liver erythrocytosis was found. What is the principal reason of increase of erythrocytes amount in this state? - a. Hyperproduction of erythropoietin - b. Transport of erythrocytes from depot - c. Inhibition of erythrocytes destruction - d. Activation of protein synthesis - e. Increased use of iron by an organism **Question 2** A patient has ostheomyelitis complicated by sepsis. The body temperature during 6 days was within the limits of 39,3 - 40,4 °C. On the 7th day a critical fall of the temperature to 37,3 °C happenned and a collapse developed. What process provoked this complication? - a. Overventilation - b. Sweating - c. Toxemia - d. Tachycardia - e. Vasodilation **Question 46** At a moderate fever the temperature of body is: - a. 38-39 OC - b. More then 41 oC - c. 39-41 oC - d. 36,6 OC - e. 37-38 oC **Question 50** Fever is accompanied by: - a. Depression of antibodies formation - b. Decreasing of heart rate - c. Increasing of heart rate - d. Increasing of gastric juice secretion - e. Depression breathings **Question 27** What can result in appearance of tumour? - a. Lethal mutation of gamete - b. Unlethal mutation of somatic cell - c. Unlethal mutation of gamete - d. An unlethal mutation of somatic cell is in an embryonic period - e. Lethal mutation of somatic cell **Question 32** What is the expansive growth of tumour tissue? - a. Transfer of tumour cells into other organs with the lymph and blood flow - b. Unlimited growth - c. Germination between normal tissue and through a vascular wall - d. Surplus growth - e. Growth of tumour in the direction of surrounding healthy tissue with its shove about **Question 17** At a malaria the recurrence of fever attacks is related to: - a. Biorhythms - b. Vibrations of hypothalamus activity - c. Use of antimalarias preparations - d. Vibrations of immune reactivity - e. Recurrence of pathogenic organism development **Question 23** Experimental transplantation of tumour from one kind of animal to other kind to the animal is: - a. Explantation - b. Gomotransplantation - c. Isotransplantation - d. Induction - e. Heterotrasplantation **Question 20** The experimental sarcoma of Raus in chickens arises up as a result: - a. Heterotrasplantations - b. Inductions - c. Gomotransplantations - d. Explantations - e. Isotransplantations **Question 36** What is the type of fever when during days the indexes of body temperature vary within the limits of 38-39 °C? - a. Hyperpyretic temperature - b. High temperature - c. Subfebrile temperature - d. Normal temperature - e. Moderate temperature **Question 11** What is the type of fever when during days the indexes of body temperature vary within the limits of 39-41 °C? - a. Subfebrile temperature - b. High temperature - c. Hyperpyretic temperature - d. Moderate temperature - e. Normal temperature **Question 10** What is the type of fever, when a gradual fervescence is during set time with the subsequent litic falling it and by the protracted unfever period? - a. Febris undulans - b. Febris atypica - c. Febris recurrens - d. Febris continua - e. Febris intermittens **Question 15** A malignant tumour which takes a place from tissues of mesenchymal origin (connecting, bone, cartilaginous) is named: - a. Melanoma - b. Sarcoma - c. Meningioma - d. Carcinoma - e. Khorionepitelioma **Question 14** What disease is characterised by the fever of hectica type? - a. Lobal pneumonia - b. Recurrent typhus - c. Malaria - d. Sepsis - e. Crupose pneumonia **Question 13** Protooncogene is: - a. Gene of tumour cells genome - b. Gene of normal genome of person - c. Precursor of carcinogenic substance - d. Substance may transforms normal cell into tumorous - e. Gene- initiator of tumour developement **Question 3** What type of fever is presents, when the temperature of body sharply rises through the identical intervals of time (2 days) on a few hours, then returns to the norm? - a. Febris recurrens - b. Febris intermittens - c. Febris hectica - d. Febris continua - e. Febris remittens **Question 8** What type of fever is observed to the recurrent typhus? - a. Febris intermittens - b. Febris remittens - c. Febris recurrens - d. Febris continua - e. Febris hectica **Question 9** What disease is a fever of irregular type at with wrong and various daily allowance fluctuations in a temperature? - a. Cholecystitis - b. Malaria - c. Croupous pneumonia - d. Brucellosis - e. Recurrent typhus **Question 19** Name the type of fever, which is characterized wrong and various daily allowance fluctuations in a temperature as combination permanent, alternating, recurrent and other types of fevers? - a. Febris continua - b. Febris intermittens - c. Febris recurrens - d. Febris atypica - e. Febris undulans **Question 4** What variant of carcinogenesis stages is correct? - a. Transformation, progression, promotion - b. Promotion, transformation, progression - c. Transformation, promotion, progression - d. Progression, transformation, promotion - e. Promotion, progression, transformation **Question 19** What method of the experimental reproducing of tumours was applied in 1915, when did the Japanese scientists of Yamagiva and Ishikava first cause a tumour in an experiment, oiling the skin of ear of rabbit coal resin? - a. Induction by radionuclides - b. Explantation - c. Induction by chemical matters - d. Transplantation - e. Induction by a cell-free filtrate **Question 21** What substanse level is increased at the pheochromocytoma (the tumour which takes a place in the cerebral layer of adrenal glande? - a. Glucagon - b. Adrenalin - c. Insulin - d. Somatotropin - e. Thyroxin This appears to be a quiz on pathological physiology, with various multiple choice questions related to fever, tumors, and their associated pathologies.